| Literature DB >> 2511288 |
J Hyatt1, C Coro, S A Bergman, R L Wynn.
Abstract
Clinical antinociception is difficult to assess because of difficulties with controls and the incorporation of bias. The rabbit antinociceptive model is highly sensitive and predictive of analgesia in humans. We found that the combination of midazolam with fentanyl enhanced antinociception compared with fentanyl alone. In addition, with this model there were relatively unimportant increases in respiratory depression.Entities:
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Year: 1989 PMID： 2511288 DOI： 10.1016/0278-2391(89)90728-3
Source DB: PubMed Journal: J Oral Maxillofac Surg ISSN： 0278-2391 Impact factor: 1.895