Literature DB >> 25112854

Beyond the G-spot: clitourethrovaginal complex anatomy in female orgasm.

Emmanuele A Jannini1, Odile Buisson2, Alberto Rubio-Casillas3.   

Abstract

The search for the legendary, highly erogenous vaginal region, the Gräfenberg spot (G-spot), has produced important data, substantially improving understanding of the complex anatomy and physiology of sexual responses in women. Modern imaging techniques have enabled visualization of dynamic interactions of female genitals during self-sexual stimulation or coitus. Although no single structure consistent with a distinct G-spot has been identified, the vagina is not a passive organ but a highly dynamic structure with an active role in sexual arousal and intercourse. The anatomical relationships and dynamic interactions between the clitoris, urethra, and anterior vaginal wall have led to the concept of a clitourethrovaginal (CUV) complex, defining a variable, multifaceted morphofunctional area that, when properly stimulated during penetration, could induce orgasmic responses. Knowledge of the anatomy and physiology of the CUV complex might help to avoid damage to its neural, muscular, and vascular components during urological and gynaecological surgical procedures.

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Year:  2014        PMID: 25112854     DOI: 10.1038/nrurol.2014.193

Source DB:  PubMed          Journal:  Nat Rev Urol        ISSN: 1759-4812            Impact factor:   14.432


  53 in total

1.  Functional anatomy of the human vagina.

Authors:  G D'Amati; C R T di Gioia; L Proietti Pannunzi; D Pistilli; E Carosa; A Lenzi; E A Jannini
Journal:  J Endocrinol Invest       Date:  2003       Impact factor: 4.256

2.  The electrovaginogram: study of the vaginal electric activity and its role in the sexual act and disorders.

Authors:  Ahmed Shafik; Olfat El Sibai; Ali A Shafik; Ismail Ahmed; Randa M Mostafa
Journal:  Arch Gynecol Obstet       Date:  2003-12-18       Impact factor: 2.344

3.  Commentary on Puts' (2006) review of The Case of the Female Orgasm: Bias in the Science of Evolution.

Authors:  Kim Wallen
Journal:  Arch Sex Behav       Date:  2006-12

4.  The female prostate.

Authors:  M Zaviacic; R J Ablin
Journal:  J Natl Cancer Inst       Date:  1998-05-06       Impact factor: 13.506

5.  Anatomical relationship between urethra and clitoris.

Authors:  H E O'Connell; J M Hutson; C R Anderson; R J Plenter
Journal:  J Urol       Date:  1998-06       Impact factor: 7.450

Review 6.  The female prostate and prostate-specific antigen. Immunohistochemical localization, implications of this prostate marker in women and reasons for using the term "prostate" in the human female.

Authors:  M Zaviacic; R J Ablin
Journal:  Histol Histopathol       Date:  2000-01       Impact factor: 2.303

Review 7.  Hysterectomy improves sexual response? Addressing a crucial omission in the literature.

Authors:  Barry R Komisaruk; Eleni Frangos; Beverly Whipple
Journal:  J Minim Invasive Gynecol       Date:  2011 May-Jun       Impact factor: 4.137

8.  Type 5 phosphodiesterase expression in the human vagina.

Authors:  Giulia D'Amati; Cira R T di Gioia; Mauro Bologna; Daniela Giordano; Mauro Giorgi; Susanna Dolci; Emmanuele A Jannini
Journal:  Urology       Date:  2002-07       Impact factor: 2.649

9.  Measurement of the thickness of the urethrovaginal space in women with or without vaginal orgasm.

Authors:  Giovanni Luca Gravina; Fulvia Brandetti; Paolo Martini; Eleonora Carosa; Savino M Di Stasi; Susanna Morano; Andrea Lenzi; Emmanuele A Jannini
Journal:  J Sex Med       Date:  2008-01-21       Impact factor: 3.802

10.  Clitoral blood flow increases following vaginal pressure stimulation.

Authors:  P Lavoisier; R Aloui; M H Schmidt; A Watrelot
Journal:  Arch Sex Behav       Date:  1995-02
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  10 in total

1.  Efficacy and tolerability of a spray formulation containing Visnadine in women self-reporting sexual symptoms: a randomized double-blind placebo-controlled pilot study.

Authors:  R Bernorio; S Piloni; G Mori; A Prunas; D Bosoni; R E Nappi
Journal:  J Endocrinol Invest       Date:  2017-12-11       Impact factor: 4.256

2.  Increased Urination Urgency Exacerbates Sexual Risk-Taking Through Heightened Sexual Arousal.

Authors:  Juwon Lee; Omri Gillath
Journal:  Arch Sex Behav       Date:  2022-07-18

Review 3.  The complexity of female orgasm and ejaculation.

Authors:  Liliana Arias-Castillo; Lina García; Herney Andrés García-Perdomo
Journal:  Arch Gynecol Obstet       Date:  2022-10-08       Impact factor: 2.493

4.  Estrogen modulates epithelial progenitor cells in rat vagina.

Authors:  Ho Seok Chung; Hyun Suk Lee; Kwangsung Park
Journal:  Investig Clin Urol       Date:  2021-04-02

Review 5.  Non-pharmacological and non-surgical strategies to promote sexual recovery for men with erectile dysfunction.

Authors:  Richard Wassersug; Erik Wibowo
Journal:  Transl Androl Urol       Date:  2017-11

Review 6.  A Meta-Analysis Detailing Overall Sexual Function and Orgasmic Function in Women Undergoing Midurethral Sling Surgery for Stress Incontinence.

Authors:  Nicole Szell; Barry Komisaruk; Sue W Goldstein; Xianggui Harvey Qu; Michael Shaw; Irwin Goldstein
Journal:  Sex Med       Date:  2017-03-28       Impact factor: 2.491

7.  Validation of a Visual Analogue Scale to measure the subjective perception of orgasmic intensity in females: The Orgasmometer-F.

Authors:  Daniele Mollaioli; Stefania Di Sante; Erika Limoncin; Giacomo Ciocca; Giovanni Luca Gravina; Elisa Maseroli; Egidia Fanni; Linda Vignozzi; Mario Maggi; Andrea Lenzi; Emmanuele A Jannini
Journal:  PLoS One       Date:  2018-08-29       Impact factor: 3.240

8.  All-Trans Retinoic Acid Increases Aquaporin 3 Expression in Human Vaginal Epithelial Cells.

Authors:  Hyun-Suk Lee; Sun-Ouck Kim; Kyuyoun Ahn; Kwangsung Park
Journal:  Sex Med       Date:  2016-07-25       Impact factor: 2.491

9.  Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction.

Authors:  Gökmen Sukgen; Aşkı Ellibeş Kaya; Ebru Karagün; Eray Çalışkan
Journal:  Turk J Obstet Gynecol       Date:  2020-02-28

10.  Effects of testosterone treatment on clitoral haemodynamics in women with sexual dysfunction.

Authors:  S Cipriani; E Maseroli; V Di Stasi; I Scavello; T Todisco; G Rastrelli; M Fambrini; F Sorbi; F Petraglia; E A Jannini; M Maggi; L Vignozzi
Journal:  J Endocrinol Invest       Date:  2021-06-12       Impact factor: 4.256

  10 in total

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