Literature DB >> 25112231

Obesity: cerebral damage in obesity-associated metabolic syndrome.

Henry Rusinek1, Antonio Convit2.   

Abstract

The prevalence of the metabolic syndrome has increased in tandem with that of obesity. The metabolic syndrome is associated with structural and functional cerebral damage. A new study confirms the association between the metabolic syndrome and reduced brain volume in the absence of diabetes mellitus. Here, we highlight how vascular dysfunction potentially contributes to this brain damage.

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Year:  2014        PMID： 25112231      PMCID： PMC4425215          DOI： 10.1038/nrendo.2014.141

Source DB:  PubMed          Journal:  Nat Rev Endocrinol        ISSN： 1759-5029            Impact factor:   43.330


  10 in total

1.  Midlife blood pressure and neuritic plaques, neurofibrillary tangles, and brain weight at death: the HAAS. Honolulu-Asia aging Study.

Authors:  H Petrovitch; L R White; G Izmirilian; G W Ross; R J Havlik; W Markesbery; J Nelson; D G Davis; J Hardman; D J Foley; L J Launer
Journal:  Neurobiol Aging       Date:  2000 Jan-Feb       Impact factor: 4.673

2.  Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report.

Authors: 
Journal:  Circulation       Date:  2002-12-17       Impact factor: 29.690

Review 3.  The role of neuronal signaling in controlling cerebral blood flow.

Authors:  Carrie T Drake; Costantino Iadecola
Journal:  Brain Lang       Date:  2006-09-28       Impact factor: 2.381

Review 4.  Impact of metabolic syndrome on cognition and brain: a selected review of the literature.

Authors:  Kathy F Yates; Victoria Sweat; Po Lai Yau; Michael M Turchiano; Antonio Convit
Journal:  Arterioscler Thromb Vasc Biol       Date:  2012-09       Impact factor: 8.311

5.  Prevalence of metabolic syndrome among adults 20 years of age and over, by sex, age, race and ethnicity, and body mass index: United States, 2003-2006.

Authors:  R Bethene Ervin
Journal:  Natl Health Stat Report       Date:  2009-05-05

6.  Changes in brain weights during the span of human life: relation of brain weights to body heights and body weights.

Authors:  A S Dekaban
Journal:  Ann Neurol       Date:  1978-10       Impact factor: 10.422

Review 7.  Links between cognitive impairment in insulin resistance: an explanatory model.

Authors:  Antonio Convit
Journal:  Neurobiol Aging       Date:  2005-10-24       Impact factor: 4.673

8.  Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010.

Authors:  Katherine M Flegal; Margaret D Carroll; Brian K Kit; Cynthia L Ogden
Journal:  JAMA       Date:  2012-01-17       Impact factor: 56.272

9.  Metabolic syndrome, prediabetes, and brain abnormalities on mri in patients with manifest arterial disease: the SMART-MR study.

Authors:  Audrey M Tiehuis; Yolanda van der Graaf; Willem P T M Mali; Koen Vincken; Majon Muller; Mirjam I Geerlings
Journal:  Diabetes Care       Date:  2014-06-19       Impact factor: 19.112

10.  Obesity and metabolic syndrome and functional and structural brain impairments in adolescence.

Authors:  Po Lai Yau; Mary Grace Castro; Adrian Tagani; Wai Hon Tsui; Antonio Convit
Journal:  Pediatrics       Date:  2012-09-03       Impact factor: 7.124
  10 in total
  9 in total

1.  The development of executive function in early childhood is inversely related to change in body mass index: Evidence for an energetic tradeoff?

Authors:  Clancy Blair; Christopher W Kuzawa; Michael T Willoughby
Journal:  Dev Sci       Date:  2019-06-14

Review 2.  Notch signaling as a novel regulator of metabolism.

Authors:  Pengpeng Bi; Shihuan Kuang
Journal:  Trends Endocrinol Metab       Date:  2015-03-21       Impact factor: 12.015

3.  Quercetin, Engelitin and Caffeic Acid of Smilax china L. Polyphenols, Stimulate 3T3-L1 Adipocytes to Brown-like Adipocytes Via β3-AR/AMPK Signaling Pathway.

Authors:  Li Kong; Wenkai Zhang; Shanshan Liu; Zhen Zhong; Guodong Zheng
Journal:  Plant Foods Hum Nutr       Date:  2022-08-20       Impact factor: 4.124

4.  Emerging self-regulatory skills in childhood predict cardiometabolic risk in adolescence.

Authors:  Jessica M Dollar; Susan D Calkins; Lenka Shriver; Susan P Keane; Lilly Shanahan; Laurie Wideman
Journal:  Compr Psychoneuroendocrinol       Date:  2021-06-27

5.  Insulin resistance among obese middle-aged is associated with decreased cerebrovascular reactivity.

Authors:  Olivia H Frosch; Po Lai Yau; Ricardo S Osorio; Henry Rusinek; Pippa Storey; Antonio Convit
Journal:  Neurology       Date:  2017-06-14       Impact factor: 9.910

6.  A hypothesis linking the energy demand of the brain to obesity risk.

Authors:  Christopher W Kuzawa; Clancy Blair
Journal:  Proc Natl Acad Sci U S A       Date:  2019-06-17       Impact factor: 11.205

7.  Longitudinal trajectories of metabolic syndrome on different neurocognitive domains: a cohort study from the Taiwan biobank.

Authors:  Shou-En Wu; Wei-Liang Chen
Journal:  Aging (Albany NY)       Date:  2021-06-11       Impact factor: 5.682

Review 8.  Impact of Nutrition on Cerebral Circulation and Cognition in the Metabolic Syndrome.

Authors:  Laura Mellendijk; Maximilian Wiesmann; Amanda J Kiliaan
Journal:  Nutrients       Date:  2015-11-13       Impact factor: 5.717

9.  Alterations in white matter volume and integrity in obesity and type 2 diabetes.

Authors:  Liselotte van Bloemendaal; Richard G Ijzerman; Jennifer S Ten Kulve; Frederik Barkhof; Michaela Diamant; Dick J Veltman; Eelco van Duinkerken
Journal:  Metab Brain Dis       Date:  2016-01-27       Impact factor: 3.584
  9 in total

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