OBJECTIVE: To study a cluster of Mycobacterium wolinskyi surgical site infections (SSIs). DESIGN: Observational and case-control study. SETTING: Academic hospital. PATIENTS: Subjects who developed SSIs with M. wolinskyi following cardiothoracic surgery. METHODS: Electronic surveillance was performed for case finding as well as electronic medical record review of infected cases. Surgical procedures were observed. Medical chart review was conducted to identify risk factors. A case-control study was performed to identify risk factors for infection; Fisher exact or Kruskal-Wallis tests were used for comparisons of proportions and medians, respectively. Patient isolates were studied using pulsed-field gel electrophoresis (PFGE). Environmental microbiologic sampling was performed in operating rooms, including high-volume water sampling. RESULTS: Six definite cases of M. wolinskyi SSI following cardiothoracic surgery were identified during the outbreak period (October 1, 2008-September 30, 2011). Having cardiac surgery in operating room A was significantly associated with infection (odds ratio, 40; P = .0027). Observational investigation revealed a cold-air blaster exclusive to operating room A as well a microbially contaminated, self-contained water source used in heart-lung machines. The isolates were indistinguishable or closely related by PFGE. No environmental samples were positive for M. wolinskyi. CONCLUSIONS: No single point source was established, but 2 potential sources, including a cold-air blaster and a microbially contaminated, self-contained water system used in heart-lung machines for cardiothoracic operations, were identified. Both of these potential sources were removed, and subsequent active surveillance did not reveal any further cases of M. wolinskyi SSI.
OBJECTIVE: To study a cluster of Mycobacterium wolinskyi surgical site infections (SSIs). DESIGN: Observational and case-control study. SETTING: Academic hospital. PATIENTS: Subjects who developed SSIs with M. wolinskyi following cardiothoracic surgery. METHODS: Electronic surveillance was performed for case finding as well as electronic medical record review of infected cases. Surgical procedures were observed. Medical chart review was conducted to identify risk factors. A case-control study was performed to identify risk factors for infection; Fisher exact or Kruskal-Wallis tests were used for comparisons of proportions and medians, respectively. Patient isolates were studied using pulsed-field gel electrophoresis (PFGE). Environmental microbiologic sampling was performed in operating rooms, including high-volume water sampling. RESULTS: Six definite cases of M. wolinskyi SSI following cardiothoracic surgery were identified during the outbreak period (October 1, 2008-September 30, 2011). Having cardiac surgery in operating room A was significantly associated with infection (odds ratio, 40; P = .0027). Observational investigation revealed a cold-air blaster exclusive to operating room A as well a microbially contaminated, self-contained water source used in heart-lung machines. The isolates were indistinguishable or closely related by PFGE. No environmental samples were positive for M. wolinskyi. CONCLUSIONS: No single point source was established, but 2 potential sources, including a cold-air blaster and a microbially contaminated, self-contained water system used in heart-lung machines for cardiothoracic operations, were identified. Both of these potential sources were removed, and subsequent active surveillance did not reveal any further cases of M. wolinskyi SSI.
Authors: Arthur W Baker; Eileen K Maziarz; Sarah S Lewis; Jason E Stout; Deverick J Anderson; Peter K Smith; Jacob N Schroder; Mani A Daneshmand; Barbara D Alexander; Richard J Wallace; Daniel J Sexton; Cameron R Wolfe Journal: Clin Infect Dis Date: 2021-04-08 Impact factor: 9.079
Authors: Peter W Schreiber; Stefan P Kuster; Barbara Hasse; Cornelia Bayard; Christian Rüegg; Philipp Kohler; Peter M Keller; Guido V Bloemberg; Francesco Maisano; Dominique Bettex; Maximilian Halbe; Rami Sommerstein; Hugo Sax Journal: Emerg Infect Dis Date: 2016-10 Impact factor: 6.883
Authors: Marta Hernández-Meneses; Julian González-Martin; Daiana Agüero; Jose M Tolosana; Elena Sandoval; Carles Falces; Rodolfo San Antonio; Bárbara Vidal; Asunción Moreno; Juan Ambrosioni; Jose M Miró Journal: Infect Dis Ther Date: 2021-03-15
Authors: Rami Sommerstein; Christian Rüegg; Philipp Kohler; Guido Bloemberg; Stefan P Kuster; Hugo Sax Journal: Emerg Infect Dis Date: 2016-06-15 Impact factor: 6.883