Literature DB >> 25111010

Triterpenoids of Ganoderma theaecolum and their hepatoprotective activities.

Li-Ying Liu1, Hui Chen1, Chao Liu1, Hong-Qing Wang1, Jie Kang1, Yan Li1, Ruo-Yun Chen2.   

Abstract

Five new lanostane triterpenoids, ganoderic acid XL1 (1), ganoderic acid XL2 (2), 20-hydroxy-ganoderic acid AM1 (3), ganoderenic acid AM1 (4) and ganoderesin C (5), together with five known triterpenoids (6-10) were isolated from the fruiting bodies of Ganoderma theaecolum. Chemical structures were elucidated on the basis of spectroscopic evidence, including 1D, 2D NMR, mass spectrometric data and circular dichroism spectra. Compounds 1, 4, 5, 8, 9 and 10 (10 μM) exhibited hepatoprotective activities against DL-galactosamine-induced cell damage in HL-7702 cells.
Copyright © 2014 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Ganoderma; Ganoderma theaecolum; Hepatoprotective activity; Triterpenoids

Mesh：

Substances：

Year:  2014        PMID： 25111010     DOI： 10.1016/j.fitote.2014.08.004

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  7 in total

1.  Accelerated processing of solitary and clustered abasic site DNA damage lesions by APE1 in the presence of aqueous extract of Ganoderma lucidum.

Authors:  Bhavini Kumari; Prolay DAS; Rekha Kumari
Journal:  J Biosci       Date:  2016-06       Impact factor: 1.826

2.  The ethanol extracts of sporoderm-broken spores of Ganoderma lucidum inhibit colorectal cancer in vitro and in vivo.

Authors:  Kang Li; Kun Na; Tingting Sang; Kaikai Wu; Ying Wang; Xingya Wang
Journal:  Oncol Rep       Date:  2017-09-27       Impact factor: 3.906

3.  Triterpenoids and polysaccharide peptides-enriched Ganoderma lucidum: a randomized, double-blind placebo-controlled crossover study of its antioxidation and hepatoprotective efficacy in healthy volunteers.

Authors:  Hui-Fang Chiu; Hui-Yu Fu; Yan-Ying Lu; Yi-Chun Han; You-Cheng Shen; Kamesh Venkatakrishnan; Oksana Golovinskaia; Chin-Kun Wang
Journal:  Pharm Biol       Date:  2017-12       Impact factor: 3.503

4.  Three new lanostanoids from the mushroom Ganoderma tropicum.

Authors:  Shuang-Shuang Zhang; Yu-Guang Wang; Qing-Yun Ma; Sheng-Zhuo Huang; Li-Li Hu; Hao-Fu Dai; Zhi-Fang Yu; You-Xing Zhao
Journal:  Molecules       Date:  2015-02-16       Impact factor: 4.411

5.  Development of Global Chemical Profiling for Quality Assessment of Ganoderma Species by ChemPattern Software.

Authors:  Hui Zhang; Huijie Jiang; Xiaojing Zhang; Shengqiang Tong; Jizhong Yan
Journal:  J Anal Methods Chem       Date:  2018-03-04       Impact factor: 2.193

6.  Isolation, Structural Elucidation, and α-Glucosidase Inhibitory Activities of Triterpenoid Lactones and Their Relevant Biogenetic Constituents from Ganoderma resinaceum.

Authors:  Xian-Qiang Chen; Li-Gen Lin; Jing Zhao; Ling-Xiao Chen; Yu-Ping Tang; De-Lun Luo; Shao-Ping Li
Journal:  Molecules       Date:  2018-06-08       Impact factor: 4.411

7.  Lanostane Triterpenoid Metabolites from a Penares sp. Marine Sponge Protect Neuro-2a Cells against Paraquat Neurotoxicity.

Authors:  Ekaterina A Yurchenko; Sophia A Kolesnikova; Ekaterina G Lyakhova; Ekaterina S Menchinskaya; Evgeny A Pislyagin; Ekaterina A Chingizova; Dmitry L Aminin
Journal:  Molecules       Date:  2020-11-18       Impact factor: 4.411
  7 in total

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