Literature DB >> 2511067

Transient exposure to a physiologically-relevant concentration of calcium confers tobramycin resistance upon sessile cells of Pseudomonas aeruginosa.

B D Hoyle1, J W Costerton.   

Abstract

Sessile populations of a mucoid Pseudomonas aeruginosa isolate generated in M-56 medium of 'low' (0.02 mM) or 'high' (2.5 mM) Ca2+ were treated with tobramycin (250 micrograms.ml-1), as were biofilms exposed transiently to 'high' Ca2+ medium. Viability decreased by over 99.9% within 8 h in the 'low' and 'high' samples, while transient Ca2+ exposure was protective. Dispersed sessile bacteria were as tobramycin sensitive as planktonic bacteria.

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Year:  1989        PMID： 2511067     DOI： 10.1016/0378-1097(89)90421-7

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN： 0378-1097            Impact factor:   2.742


  6 in total

1.  Calcium-induced virulence factors associated with the extracellular matrix of mucoid Pseudomonas aeruginosa biofilms.

Authors:  S Sarkisova; M A Patrauchan; D Berglund; D E Nivens; M J Franklin
Journal:  J Bacteriol       Date:  2005-07       Impact factor: 3.490

2.  Training the Biofilm Generation--a tribute to J. W. Costerton.

Authors:  Robert J C McLean; Joseph S Lam; Lori L Graham
Journal:  J Bacteriol       Date:  2012-09-07       Impact factor: 3.490

Review 3.  Polypropylene mesh and the host response.

Authors:  Hiren Patel; Donald R Ostergard; Gina Sternschuss
Journal:  Int Urogynecol J       Date:  2012-03-20       Impact factor: 2.894

4.  Interaction between biofilms formed by Pseudomonas aeruginosa and clarithromycin.

Authors:  H Yasuda; Y Ajiki; T Koga; H Kawada; T Yokota
Journal:  Antimicrob Agents Chemother       Date:  1993-09       Impact factor: 5.191

5.  Production of mucoid exopolysaccharide during development of Pseudomonas aeruginosa biofilms.

Authors:  B D Hoyle; L J Williams; J W Costerton
Journal:  Infect Immun       Date:  1993-02       Impact factor: 3.441

6.  Pseudomonas aeruginosa biofilm as a diffusion barrier to piperacillin.

Authors:  B D Hoyle; J Alcantara; J W Costerton
Journal:  Antimicrob Agents Chemother       Date:  1992-09       Impact factor: 5.191
  6 in total

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