Literature DB >> 25110438

Surgical management of colonic diverticular disease: discrepancy between right- and left-sided diseases.

Heung-Kwon Oh1, Eon Chul Han1, Heon-Kyun Ha1, Eun Kyung Choe1, Sang Hui Moon1, Seung-Bum Ryoo1, Seung-Yong Jeong1, Kyu Joo Park1.   

Abstract

AIM: To compare the outcome of the surgical management of left-sided and right-sided diverticular disease.
METHODS: The medical records of 77 patients who were surgically treated for diverticular disease between 1999 and 2010 in a tertiary referral hospital were retrospectively reviewed. The study population was limited to cases wherein the surgical specimen was confirmed as diverticulosis by pathology. Right-sided diverticula were classified as those arising from the cecum, ascending colon, and transverse colon, and those from the descending colon, sigmoid colon, and rectum were classified as left-sided diverticulosis. To assess the changing trend of occurrence of diverticulosis, data were compared with two previous studies of 51 patients.
RESULTS: The proportion of left-sided disease cases was significantly increased compared to the results of our previous studies in 1994 and 2001, (27.5% vs 48.1%, P < 0.05). Moreover, no differences in gender, body mass index, multiplicity of the diverticula, fever, or leukocytosis were noted between patients with right-sided and left-sided disease. However, patients with right-sided disease were significantly younger (50.9 year vs 64.0 year, P < 0.01). Furthermore, left-sided disease was significantly associated with a higher incidence of complicated diverticulitis (89.2% vs 57.5%, P < 0.01), combined resection due to extensive inflammation (21.6% vs 5.0%, P < 0.05), operative complications (51.4% vs 27.5%, P < 0.05), and in-hospital mortality (10.8% vs 0%, P < 0.05), along with longer post-operative hospitalization duration (21.3 ± 10.2 d vs 10.6 ± 8.1 d, P < 0.05).
CONCLUSION: Compared with right-sided diverticular disease, the incidence of left-sided disease in Korea has increased since 2001 and is associated with worse surgical outcomes.

Entities:  

Keywords:  Colonic diverticulosis; Diverticular bleeding; Diverticulitis; Left-sided diverticulitis; Poor surgical outcome

Mesh:

Year:  2014        PMID: 25110438      PMCID: PMC4123340          DOI: 10.3748/wjg.v20.i29.10115

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


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  14 in total

1.  Short- and Long-Term Outcomes of Right-Sided Diverticulitis: Over 15 Years of North American Experience.

Authors:  Jesse Zuckerman; Richard Garfinkle; Carol-Ann Vasilevksy; Gabriela Ghitulescu; Julio Faria; Nancy Morin; Marylise Boutros
Journal:  World J Surg       Date:  2020-06       Impact factor: 3.352

2.  Perforated diverticulitis: is the right and left difference present here too?

Authors:  Nicholas Yock Teck Soh; Nan Zun Teo; Carrie Jen Hsi Tan; Shivani Rajaraman; Marianne Tsang; Calvin Jian Ming Ong; Ramesh Wijaya
Journal:  Int J Colorectal Dis       Date:  2018-03-12       Impact factor: 2.571

3.  Conservative treatment of uncomplicated right-sided diverticulitis: a systematic review and meta-analysis.

Authors:  Jun Ho Lee; Byung Kyu Ahn; Kang Hong Lee
Journal:  Int J Colorectal Dis       Date:  2021-03-25       Impact factor: 2.571

4.  Prospective randomized clinical trial of uncomplicated right-sided colonic diverticulitis: antibiotics versus no antibiotics.

Authors:  Jeong Yeon Kim; Sung Gil Park; Hee Joon Kang; Young Ah Lim; Kyung Ho Pak; Tae Yoo; Won Tae Cho; Dong Woo Shin; Jong Wan Kim
Journal:  Int J Colorectal Dis       Date:  2019-07-02       Impact factor: 2.571

5.  Short-term outcomes following resection of right colon diverticulitis: a comparison of open and minimally invasive approaches using the NSQIP database.

Authors:  Michael L Horsey; Richard Amdur; Matthew Ng; Vincent J Obias
Journal:  Surg Endosc       Date:  2021-10-25       Impact factor: 3.453

Review 6.  The Burden of Diverticular Disease and Its Complications: West versus East.

Authors:  Hiroyuki Imaeda; Toshifumi Hibi
Journal:  Inflamm Intest Dis       Date:  2018-08-07

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Authors:  Yoshiharu Uno; Jennifer C van Velkinburgh
Journal:  World J Gastrointest Pharmacol Ther       Date:  2016-11-06

8.  Predictive Factors Affecting the Clinical Course of Patients With Diverticulitis: Who Needs Hospital Management?

Authors:  Taeyoung Yoo; Keun Ho Yang; Jungbin Kim; Inseok Park; Hyunjin Cho; Geumhee Gwak; Byung Noe Bae; Ki Hwan Kim
Journal:  Ann Coloproctol       Date:  2018-02-28

9.  Right-Sided Colonic Diverticulitis: Clinical Features, Sonographic Appearances, and Management.

Authors:  Tse-Cheng Chiu; Yi-Hong Chou; Chui-Mei Tiu; Hong-Jen Chiou; Hsin-Kai Wang; Yi-Chen Lai; Yi-You Chiou
Journal:  J Med Ultrasound       Date:  2017-02-10

10.  Clinical Features and Factors Associated With Surgical Treatment in Patients With Complicated Colonic Diverticulitis.

Authors:  Pill Sun Paik; Jung-A Yun
Journal:  Ann Coloproctol       Date:  2017-10-31
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