Literature DB >> 25110012

Deregulated coenzyme A, loss of metabolic flexibility and diabetes.

Suzanne Jackowski1, Roberta Leonardi2.   

Abstract

CoA (coenzyme A) is an essential cofactor that is emerging as a global regulator of energy metabolism. Tissue CoA levels are tightly regulated and vary in response to different conditions including nutritional state and diabetes. Recent studies reveal the ability of this cofactor to control the output of key metabolic pathways. CoA regulation is important for the maintenance of metabolic flexibility and glucose homoeostasis.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 25110012      PMCID： PMC4950865          DOI： 10.1042/BST20140156

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


  34 in total

Review 1.  Hepatic triacylglycerol accumulation and insulin resistance.

Authors:  Cynthia A Nagle; Eric L Klett; Rosalind A Coleman
Journal:  J Lipid Res       Date:  2008-11-06       Impact factor: 5.922

2.  Increased insulin sensitivity in mice lacking p85beta subunit of phosphoinositide 3-kinase.

Authors:  Kohjiro Ueki; Claudine M Yballe; Saskia M Brachmann; David Vicent; John M Watt; C Ronald Kahn; Lewis C Cantley
Journal:  Proc Natl Acad Sci U S A       Date:  2001-12-18       Impact factor: 11.205

Review 3.  On acetyl-CoA as a gauge of cellular metabolic state.

Authors:  L Cai; B P Tu
Journal:  Cold Spring Harb Symp Quant Biol       Date:  2011-09-06

4.  The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.

Authors:  Li Yang; Bhavapriya Vaitheesvaran; Kirsten Hartil; Alan J Robinson; Michael R Hoopmann; Jimmy K Eng; Irwin J Kurland; James E Bruce
Journal:  J Proteome Res       Date:  2011-08-16       Impact factor: 4.466

5.  Diacylglycerol-mediated insulin resistance.

Authors:  Derek M Erion; Gerald I Shulman
Journal:  Nat Med       Date:  2010-04       Impact factor: 53.440

6.  Regulation of cellular metabolism by protein lysine acetylation.

Authors:  Shimin Zhao; Wei Xu; Wenqing Jiang; Wei Yu; Yan Lin; Tengfei Zhang; Jun Yao; Li Zhou; Yaxue Zeng; Hong Li; Yixue Li; Jiong Shi; Wenlin An; Susan M Hancock; Fuchu He; Lunxiu Qin; Jason Chin; Pengyuan Yang; Xian Chen; Qunying Lei; Yue Xiong; Kun-Liang Guan
Journal:  Science       Date:  2010-02-19       Impact factor: 47.728

7.  Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.

Authors:  David B Savage; Cheol Soo Choi; Varman T Samuel; Zhen-Xiang Liu; Dongyan Zhang; Amy Wang; Xian-Man Zhang; Gary W Cline; Xing Xian Yu; John G Geisler; Sanjay Bhanot; Brett P Monia; Gerald I Shulman
Journal:  J Clin Invest       Date:  2006-02-16       Impact factor: 14.808

Review 8.  Hepatocytes: critical for glucose homeostasis.

Authors:  Peter J Klover; Robert A Mooney
Journal:  Int J Biochem Cell Biol       Date:  2004-05       Impact factor: 5.085

9.  Impaired Coenzyme A metabolism affects histone and tubulin acetylation in Drosophila and human cell models of pantothenate kinase associated neurodegeneration.

Authors:  Katarzyna Siudeja; Balaji Srinivasan; Lanjun Xu; Anil Rana; Jannie de Jong; Ellen A A Nollen; Suzanne Jackowski; Lynn Sanford; Susan Hayflick; Ody C M Sibon
Journal:  EMBO Mol Med       Date:  2011-10-14       Impact factor: 12.137

10.  Germline deletion of pantothenate kinases 1 and 2 reveals the key roles for CoA in postnatal metabolism.

Authors:  Matthew Garcia; Roberta Leonardi; Yong-Mei Zhang; Jerold E Rehg; Suzanne Jackowski
Journal:  PLoS One       Date:  2012-07-17       Impact factor: 3.240
View more
  12 in total

1.  Mechanistic basis for impaired ferroptosis in cells expressing the African-centric S47 variant of p53.

Authors:  Julia I-Ju Leu; Maureen E Murphy; Donna L George
Journal:  Proc Natl Acad Sci U S A       Date:  2019-04-08       Impact factor: 11.205

2.  Extensive metabolic remodeling after limiting mitochondrial lipid burden is consistent with an improved metabolic health profile.

Authors:  Sujoy Ghosh; Shawna E Wicks; Bolormaa Vandanmagsar; Tamra M Mendoza; David S Bayless; J Michael Salbaum; Stephen P Dearth; Shawn R Campagna; Randall L Mynatt; Robert C Noland
Journal:  J Biol Chem       Date:  2019-05-16       Impact factor: 5.157

3.  Nudt19 is a renal CoA diphosphohydrolase with biochemical and regulatory properties that are distinct from the hepatic Nudt7 isoform.

Authors:  Stephanie A Shumar; Evan W Kerr; Werner J Geldenhuys; Grace E Montgomery; Paolo Fagone; Puchong Thirawatananond; Harry Saavedra; Sandra B Gabelli; Roberta Leonardi
Journal:  J Biol Chem       Date:  2018-01-29       Impact factor: 5.157

4.  Carnitine acetyltransferase (Crat) in hunger-sensing AgRP neurons permits adaptation to calorie restriction.

Authors:  Alex Reichenbach; Romana Stark; Mathieu Mequinion; Sarah H Lockie; Moyra B Lemus; Randall L Mynatt; Serge Luquet; Zane B Andrews
Journal:  FASEB J       Date:  2018-06-22       Impact factor: 5.191

5.  The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity.

Authors:  Konrad J Mostert; Nandini Sharma; Marianne van der Zwaag; Roxine Staats; Lizbé Koekemoer; Ruchi Anand; Ody C M Sibon; Erick Strauss
Journal:  ACS Chem Biol       Date:  2021-09-28       Impact factor: 5.100

Review 6.  Acetyl-CoA and the regulation of metabolism: mechanisms and consequences.

Authors:  Lei Shi; Benjamin P Tu
Journal:  Curr Opin Cell Biol       Date:  2015-02-20       Impact factor: 8.382

7.  Determination of Coenzyme A and Acetyl-Coenzyme A in Biological Samples Using HPLC with UV Detection.

Authors:  Yevgeniya I Shurubor; Marilena D'Aurelio; Joanne Clark-Matott; Elena P Isakova; Yulia I Deryabina; M Flint Beal; Arthur J L Cooper; Boris F Krasnikov
Journal:  Molecules       Date:  2017-08-23       Impact factor: 4.411

8.  Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening.

Authors:  Efrat Resnick; Anthony Bradley; Jinrui Gan; Alice Douangamath; Tobias Krojer; Ritika Sethi; Paul P Geurink; Anthony Aimon; Gabriel Amitai; Dom Bellini; James Bennett; Michael Fairhead; Oleg Fedorov; Ronen Gabizon; Jin Gan; Jingxu Guo; Alexander Plotnikov; Nava Reznik; Gian Filippo Ruda; Laura Díaz-Sáez; Verena M Straub; Tamas Szommer; Srikannathasan Velupillai; Daniel Zaidman; Yanling Zhang; Alun R Coker; Christopher G Dowson; Haim M Barr; Chu Wang; Kilian V M Huber; Paul E Brennan; Huib Ovaa; Frank von Delft; Nir London
Journal:  J Am Chem Soc       Date:  2019-05-22       Impact factor: 15.419

Review 9.  The Pathophysiological Role of CoA.

Authors:  Aleksandra Czumaj; Sylwia Szrok-Jurga; Areta Hebanowska; Jacek Turyn; Julian Swierczynski; Tomasz Sledzinski; Ewa Stelmanska
Journal:  Int J Mol Sci       Date:  2020-11-28       Impact factor: 5.923

10.  Peroxisome Proliferator-Activated Receptor γ2 Controls the Rate of Adipose Tissue Lipid Storage and Determines Metabolic Flexibility.

Authors:  Sam Virtue; Kasparas Petkevicius; José Maria Moreno-Navarrete; Benjamin Jenkins; Daniel Hart; Martin Dale; Albert Koulman; José Manuel Fernández-Real; Antonio Vidal-Puig
Journal:  Cell Rep       Date:  2018-08-21       Impact factor: 9.423
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.