Literature DB >> 25109279

Cross-talk between SIRT1 and endocrine factors: effects on energy homeostasis.

Mar Quiñones1, Omar Al-Massadi2, Johan Fernø3, Ruben Nogueiras4.   

Abstract

The mammalian sirtuins (SIRT1-7) are a family of highly conserved nicotine adenine dinucleotide (NAD(+))-dependent deacetylases that act as cellular sensors to detect energy availability. SIRT1 is a multifaceted protein that is involved in a wide variety of cellular processes. SIRT1 is activated in response to caloric restriction, acting on multiple targets in a wide range of tissues. SIRT1 regulates the role of multiple hormones implicated in energy balance, including glucose and lipid metabolism. Here, we review the relevant role of SIRT1 as a mediator of endocrine function of several hormones to modulate energy balance. In addition, we analyze the potential of targeting SIRT1 for the treatment of obesity and type 2 diabetes mellitus.
Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Food intake; Hormones; Insulin; Obesity; SIRT1

Mesh：

Substances：

Year:  2014        PMID： 25109279     DOI： 10.1016/j.mce.2014.08.002

Source DB:  PubMed          Journal:  Mol Cell Endocrinol        ISSN： 0303-7207            Impact factor:   4.102


  8 in total

1.  Tissue-specific gene expression and fasting regulation of sirtuin family in gilthead sea bream (Sparus aurata).

Authors:  Paula Simó-Mirabet; Azucena Bermejo-Nogales; Josep Alvar Calduch-Giner; Jaume Pérez-Sánchez
Journal:  J Comp Physiol B       Date:  2016-07-18       Impact factor: 2.200

Review 2.  Metabolism disrupting chemicals and metabolic disorders.

Authors:  Jerrold J Heindel; Bruce Blumberg; Mathew Cave; Ronit Machtinger; Alberto Mantovani; Michelle A Mendez; Angel Nadal; Paola Palanza; Giancarlo Panzica; Robert Sargis; Laura N Vandenberg; Frederick Vom Saal
Journal:  Reprod Toxicol       Date:  2016-10-17       Impact factor: 3.143

3.  Plasma levels of SIRT1 associate with non-alcoholic fatty liver disease in obese patients.

Authors:  Stefania Mariani; Daniela Fiore; Sabrina Basciani; Agnese Persichetti; Savina Contini; Carla Lubrano; Luisa Salvatori; Andrea Lenzi; Lucio Gnessi
Journal:  Endocrine       Date:  2014-10-31       Impact factor: 3.633

4.  Circulating SIRT1 Increases After Intragastric Balloon Fat Loss in Obese Patients.

Authors:  Stefania Mariani; Daniela Fiore; Agnese Persichetti; Sabrina Basciani; Carla Lubrano; Eleonora Poggiogalle; Alfredo Genco; Lorenzo Maria Donini; Lucio Gnessi
Journal:  Obes Surg       Date:  2016-06       Impact factor: 4.129

5.  Electroacupuncture: A Feasible Sirt1 Promoter Which Modulates Metainflammation in Diet-Induced Obesity Rats.

Authors:  Dan Luo; Li Liu; Feng-Xia Liang; Zhao-Min Yu; Rui Chen
Journal:  Evid Based Complement Alternat Med       Date:  2018-10-22       Impact factor: 2.629

6.  Association Between SIRT1, Cytokines, and Metabolic Syndrome in Schizophrenia Patients With Olanzapine or Clozapine Monotherapy.

Authors:  Xinyu Fang; Lingfang Yu; Dandan Wang; Yan Chen; Yewei Wang; Zenan Wu; Ruimei Liu; Juanjuan Ren; Wei Tang; Chen Zhang
Journal:  Front Psychiatry       Date:  2020-11-25       Impact factor: 4.157

7.  SESN1 attenuates the Ox‑LDL‑induced inflammation, apoptosis and endothelial‑mesenchymal transition of human umbilical vein endothelial cells by regulating AMPK/SIRT1/LOX1 signaling.

Authors:  Feng Gao; Yongcheng Zhao; Bin Zhang; Chunwei Xiao; Zhanfa Sun; Yuan Gao; Xueyong Dou
Journal:  Mol Med Rep       Date:  2022-03-16       Impact factor: 3.423

8.  In Patients with Coronary Artery Disease and Type 2 Diabetes, SIRT1 Expression in Circulating Mononuclear Cells Is Associated with Levels of Inflammatory Cytokines but Not with Coronary Lesions.

Authors:  Yuanmin Li; Jing Ni; Rong Guo; Weiming Li
Journal:  Biomed Res Int       Date:  2016-03-31       Impact factor: 3.411
  8 in total

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