Literature DB >> 25105534

Desymmetrization of meso-aziridines with TMSNCS using metal salts of novel chiral imidazoline-phosphoric acid catalysts.

Shuichi Nakamura1, Mutsuyo Ohara, Madoka Koyari, Masashi Hayashi, Kengo Hyodo, Nadaf Rashid Nabisaheb, Yasuhiro Funahashi.   

Abstract

Highly enantioselective desymmetrization of aziridines with TMSNCS has been developed. Good yield and enantioselectivity were observed by using novel chiral imidazoline-phosphoric acid catalysts. The obtained product can be converted to a chiral β-aminothiol and a β-aminosulfonic acid.

Entities:  

Year:  2014        PMID: 25105534     DOI: 10.1021/ol501990t

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

Review 1.  Nucleophilic ring opening reactions of aziridines.

Authors:  Rabia Akhtar; Syed Ali Raza Naqvi; Ameer Fawad Zahoor; Sameera Saleem
Journal:  Mol Divers       Date:  2018-05-04       Impact factor: 2.943

  1 in total

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