| Literature DB >> 25105303 |
Yongda Zhang1, Bruce Z Lu, Guisheng Li, Sonia Rodriguez, Jonathan Tan, Han-Xun Wei, Jianxiu Liu, Frank Roschangar, Fei Ding, Wenyi Zhao, Bo Qu, Diana Reeves, Nelu Grinberg, Heewon Lee, Golo Heckmann, Oliver Niemeier, Michael Brenner, Youla Tsantrizos, Pierre L Beaulieu, Azad Hossain, Nathan Yee, Vittorio Farina, Chris H Senanayake.
Abstract
A highly concise and convergent synthesis of HCV polymerase inhibitor Deleobuvir (BI 207127, 1) was achieved, featuring efficient Pd-catalyzed one-pot borylation-Suzuki coupling where TFP was identified as the unique ligand effective for these transformations.Entities:
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Year: 2014 PMID： 25105303 DOI： 10.1021/ol5021114
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005