A Maudgil1, B E Wagner2, P Rundle1, I G Rennie3, H S Mudhar4. 1. Department of Ophthalmology, Royal Hallamshire Hospital , Sheffield, UK. 2. Electron Microscopy Unit, Department of Histopathology, Royal Hallamshire Hospital, Sheffield, UK. 3. Academic Unit of Ophthalmology & Orthoptics, The University of Sheffield, Sheffield, UK. 4. National Specialist Ophthalmic Pathology Service (NSOPS)-Department of Histopathology, Royal Hallamshire Hospital, Sheffield, UK.
Abstract
PURPOSE: Malignant melanoma of the eye is an uncommon condition that is important to recognise. We describe three cases in which ocular foreign bodies have masqueraded as ocular malignant melanoma. METHODS: Interventional case reports. RESULTS: Case 1 describes diathermy-induced carbon particle implantation, during plaque therapy for the treatment of uveal melanoma, mimicking recurrence with extra-scleral invasion. Case 2 shows a foreign body called 'mullite' mimicking conjunctival melanoma. Case 3 demonstrates a conjunctival foreign body called 'illite' that mimicked a limbal melanocytic lesion, clinically thought to be either melanocytoma or melanoma. CONCLUSION: This report highlights the importance of careful history taking, examination, and appropriate biopsy in cases of suspected malignant melanoma, to prevent unnecessary and potentially radical treatment.
PURPOSE:Malignant melanoma of the eye is an uncommon condition that is important to recognise. We describe three cases in which ocular foreign bodies have masqueraded as ocular malignant melanoma. METHODS: Interventional case reports. RESULTS: Case 1 describes diathermy-induced carbon particle implantation, during plaque therapy for the treatment of uveal melanoma, mimicking recurrence with extra-scleral invasion. Case 2 shows a foreign body called 'mullite' mimicking conjunctival melanoma. Case 3 demonstrates a conjunctival foreign body called 'illite' that mimicked a limbal melanocytic lesion, clinically thought to be either melanocytoma or melanoma. CONCLUSION: This report highlights the importance of careful history taking, examination, and appropriate biopsy in cases of suspected malignant melanoma, to prevent unnecessary and potentially radical treatment.
Authors: Pablo Zoroquiain; Maria Sb Ganimi; Sarah Alghamdi; Julia V Burnier; Sultan S Aldrees; Miguel N Burnier Journal: Ecancermedicalscience Date: 2016-02-12