| Literature DB >> 25103863 |
Yusuke Kawano1, Iwao Ohtsu2, Kazuhiro Takumi3, Ai Tamakoshi1, Gen Nonaka3, Eri Funahashi1, Masaki Ihara4, Hiroshi Takagi1.
Abstract
Using in silico analysis, the yciW gene of Escherichia coli was identified as a novel L-cysteine regulon that may be regulated by the transcriptional activator CysB for sulfur metabolic genes. We found that overexpression of yciW conferred tolerance to L-cysteine, but disruption of yciW increased L-cysteine production in E. coli.Entities:
Keywords: CysB-binding motif; Escherichia coli; In silico analysis; l-Cysteine fermentation; yciW gene
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Year: 2014 PMID： 25103863 DOI： 10.1016/j.jbiosc.2014.07.006
Source DB: PubMed Journal: J Biosci Bioeng ISSN： 1347-4421 Impact factor: 2.894