Literature DB >> 25103717

Operative resection is a viable treatment of macrodactyly of the foot caused by lipofibromatous hamartoma: a case study with 5 year follow-up.

Bas L Fransen1, Maud G J Broeders2, Frederik J T van Oosterom3, Nathalie D B Gilhuijs4, Bart J Burger2.   

Abstract

UNLABELLED: Lipofibromatous hamartoma (LFH) is a benign tumour of nervous tissue that most commonly involves the median nerve. Only a few cases of LFH in the foot have been described. In these cases growth of bone and other tissue causing macrodactyly, a condition known as macrodystrophia lipomatosa, is often observed. Conservative treatment of LFH is usually preferred because of the potential loss of neurological function after surgery. Here we present a rare case of a 44-year old patient with LFH causing macrodactyly of the second ray of the left foot whose symptoms did not improve after conservative treatment. We describe the diagnostic process and the operative resection that was performed and show the follow-up results 5 years after surgery. All the symptoms experienced by our patient had disappeared. This case demonstrates that operative treatment of LFH in the foot is a viable option in patients with persistent symptoms following conservative treatment. LEVEL OF EVIDENCE: Level V.
Copyright © 2014 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Forefoot disorders; Lipofibromatous hamartoma; Macrodactyly; Macrodystrophia lipomatosa; Paediatric; Tumours

Mesh:

Year:  2014        PMID: 25103717     DOI: 10.1016/j.fas.2014.05.002

Source DB:  PubMed          Journal:  Foot Ankle Surg        ISSN: 1268-7731            Impact factor:   2.705


  3 in total

1.  Use of Ultra-high-frequency Ultrasound on Diagnosis and Management of Lipofibromatous Hamartoma: A Technical Report.

Authors:  Daniel Boczar; Antonio J Forte; Luiza P Serrano; Stephen D Trigg; Steven R Clendenen
Journal:  Cureus       Date:  2019-09-30

2.  Activating PIK3CA mutation promotes adipogenesis of adipose-derived stem cells in macrodactyly via up-regulation of E2F1.

Authors:  Bin Sun; Yongkang Jiang; Hengqing Cui; Xia Fang; Gang Han; Xinyi Dai; Shengbo Zhou; Hailei Mao; Bin Wang
Journal:  Cell Death Dis       Date:  2020-07-30       Impact factor: 8.469

3.  Morphological and neurophysiological impairment of the nerve in type II macrodactyly.

Authors:  Xi Yang; Yongkang Jiang; Shengbo Zhou; Ruiji Guo; Gang Han; Bin Wang
Journal:  PLoS One       Date:  2018-07-12       Impact factor: 3.240

  3 in total

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