Literature DB >> 25103448

Participation of pharmacists in clinical trial recruitment for low back pain.

Christina Abdel Shaheed1, Christopher G Maher, Kylie A Williams, Andrew J McLachlan.   

Abstract

INTRODUCTION: Clinician involvement in clinical trials research represents a significant contribution to addressing important research questions in primary care. AIM: This study aimed to explore the experiences of pharmacists recruiting patients to a low back pain (LBP) clinical trial conducted in Australia, the challenges they experienced and screening and management of people with acute LBP. ETHICAL APPROVAL: This study received ethical approval (No. 13799) through the University of Sydney Human Research Ethics Committee.
METHODS: A convenience sample of 15 pharmacists who successfully recruited people to the clinical trial and 15 pharmacists who collaborated on the trial but did not recruit any participants were invited to complete an open ended questionnaire. The questionnaire consisted of six items framed to evaluate pharmacists' views on participation in the LBP clinical trial, ideas for addressing the challenges they experienced and screening and management of people with LBP who present to the pharmacy.
RESULTS: A total of 30 pharmacists completed the questionnaire. Pharmacists identified lack of time and patient reluctance to participate as the major challenges to recruiting participants to the LBP clinical trial. Greater patient incentives and a more efficient paperwork system have been recommended as strategies to overcome these challenges. The recruiters and non-recruiters held similar views on pharmacological management of acute LBP and complied with guideline recommended care; although their views on the non-pharmacological management of acute LBP were less consistent with the guidelines. DISCUSSION: The experiences of pharmacists evaluated in this study has broadened the understanding around challenges to recruitment for a placebo controlled trial and identified gaps which can be addressed in future training and education of pharmacists.
CONCLUSION: This study has identified time pressure as the major barrier to recruitment of participants to the LBP clinical trial. Education of pharmacists on the appropriate non-pharmacological management of people with LBP and screening for possible red flag conditions is required.

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Year:  2014        PMID: 25103448     DOI: 10.1007/s11096-014-9985-y

Source DB:  PubMed          Journal:  Int J Clin Pharm


  28 in total

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3.  Understanding the perspectives of recruiters is key to improving randomised controlled trial enrolment: a qualitative evidence synthesis.

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4.  Building clinical trials around patients: Evaluation and comparison of decentralized and conventional site models in patients with low back pain.

Authors:  Carsten Sommer; Diego Zuccolin; Valdo Arnera; Nicole Schmitz; Pernilla Adolfsson; Nicoletta Colombo; Raphaelle Gilg; Bryan McDowell
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