Literature DB >> 25103318

Plasmablastic multiple myeloma following clear cell renal cell carcinoma.

Somanath Padhi1, Sudhagar Mokkappan2, Renu G' Boy Varghese1, Ilangovan Veerappan3.   

Abstract

We aim to describe the clinicohaematological profile of an elderly male with plasmablastic multiple myeloma (MM) (IgG λ, International System Stage II) with an unfavourable outcome following chemotherapy. The serum interleukin-6 level was found to be markedly elevated (2464 pg/mL, reference; <50 pg/mL). Thirty-six months prior to MM diagnosis, he underwent left radical nephrectomy for a stage III (pT3N0M0) clear cell renal cell carcinoma (RCC, Fuhrman grade 2). The unique MM-RCC association, shared risk factors, myeloma pathobiology and clinical implications are discussed with a brief literature review. 2014 BMJ Publishing Group Ltd.

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Year:  2014        PMID: 25103318      PMCID: PMC4127752          DOI: 10.1136/bcr-2014-204778

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  11 in total

1.  Interleukin-6 produced by renal-cell carcinoma cells and progression of multiple myeloma.

Authors:  A Sakai; M Kawano; A Kuramoto
Journal:  N Engl J Med       Date:  1991-06-27       Impact factor: 91.245

2.  The association between renal cell carcinoma and multiple myeloma: insights from population-based data.

Authors:  Rohit P Ojha; Eva L Evans; Martha J Felini; Karan P Singh; Raymond Thertulien
Journal:  BJU Int       Date:  2010-11-23       Impact factor: 5.588

3.  Multiple primary malignancies in patients with renal cell carcinoma: a national population-based cohort study.

Authors:  Christian Beisland; Olaug Talleraas; August Bakke; Jarle Norstein
Journal:  BJU Int       Date:  2006-04       Impact factor: 5.588

4.  Multiple myeloma and renal cell carcinoma possible association.

Authors:  Ashraf Badros; Joyson Karakunnel; Nancy Dawson
Journal:  Leuk Lymphoma       Date:  2007-08

Review 5.  Multiple myeloma.

Authors:  Antonio Palumbo; Kenneth Anderson
Journal:  N Engl J Med       Date:  2011-03-17       Impact factor: 91.245

Review 6.  Synchronous renal cell carcinoma and multiple myeloma: report of two cases and review of the literature.

Authors:  M A Ozturk; F Dane; I Kaygusuz; O Asmaz; A Uzay; M Bayik; N S Turhal
Journal:  J BUON       Date:  2009 Jul-Sep       Impact factor: 2.533

7.  Fine-needle aspiration biopsy of multiple myeloma in a patient with renal-cell carcinoma: a case report.

Authors:  G L Cooper; D W Shaffer; H B Raval
Journal:  Diagn Cytopathol       Date:  1993-10       Impact factor: 1.582

8.  Association between renal cell carcinoma and plasma cell dyscrasias: a case series of six patients.

Authors:  Meghana S Bhandari; Amitabha Mazumder; Sundar Jagannath; David H Vesole
Journal:  Clin Lymphoma Myeloma       Date:  2008-06

9.  Cyclin D1 expression in multiple myeloma by immunohistochemistry: Case series of 14 patients and literature review.

Authors:  Somanath Padhi; Renu G'boy Varghese; Anita Ramdas
Journal:  Indian J Med Paediatr Oncol       Date:  2013-10

10.  c-Met signaling promotes IL-6-induced myeloma cell proliferation.

Authors:  Håkon Hov; Erming Tian; Toril Holien; Randi Utne Holt; Thea K Våtsveen; Unn-Merete Fagerli; Anders Waage; Magne Børset; Anders Sundan
Journal:  Eur J Haematol       Date:  2009-01-06       Impact factor: 2.997

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  2 in total

Review 1.  Coexistence of multiple myeloma and clear cell renal cell carcinoma: a case report and review of literature.

Authors:  Gaixiang Xu; Min Yang; Jian Huang; Jie Jin
Journal:  Int J Clin Exp Pathol       Date:  2015-06-01

2.  A patient with Multiple myeloma and Renal cell carcinoma.

Authors:  Farhad Shahi; Marziye Ghalamkari; Mehrzad Mirzania; Mahdi Khatuni
Journal:  Int J Hematol Oncol Stem Cell Res       Date:  2016-01-01
  2 in total

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