| Literature DB >> 25103318 |
Somanath Padhi1, Sudhagar Mokkappan2, Renu G' Boy Varghese1, Ilangovan Veerappan3.
Abstract
We aim to describe the clinicohaematological profile of an elderly male with plasmablastic multiple myeloma (MM) (IgG λ, International System Stage II) with an unfavourable outcome following chemotherapy. The serum interleukin-6 level was found to be markedly elevated (2464 pg/mL, reference; <50 pg/mL). Thirty-six months prior to MM diagnosis, he underwent left radical nephrectomy for a stage III (pT3N0M0) clear cell renal cell carcinoma (RCC, Fuhrman grade 2). The unique MM-RCC association, shared risk factors, myeloma pathobiology and clinical implications are discussed with a brief literature review. 2014 BMJ Publishing Group Ltd.Entities:
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Year: 2014 PMID: 25103318 PMCID: PMC4127752 DOI: 10.1136/bcr-2014-204778
Source DB: PubMed Journal: BMJ Case Rep ISSN: 1757-790X