Literature DB >> 25103314

A rare case of acute hepatitis induced by use of Babchi seeds as an Ayurvedic remedy for vitiligo.

Deborah Ann Smith1, Stewart MacDonald2.   

Abstract

This case highlights that hepatitis is a potential side effect of Babchi seeds, an Ayurvedic remedy used to treat vitiligo. The patient, a 52-year-old Indian woman, presented with a 1 week history of jaundice, vomiting, pruritus and abdominal pain. Progressive deterioration in liver function prompted a liver biopsy which was consistent with the diagnosis of a drug-induced hepatitis. The hepatitis resolved after withdrawal of its use. A PubMed search found no previous UK cases and only two cases have been reported globally. This potentially serious side effect of a widely available substance is not acknowledged by manufacturers, and those purchasing the product are unaware of the risk of harm. To compound this risk, there is an absence of dosing advice or maximum recommended daily intake. It is important to ask about topical and oral herbal remedies in cases of acute jaundice as patients rarely perceive these preparations as 'medications'. 2014 BMJ Publishing Group Ltd.

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Year:  2014        PMID: 25103314      PMCID: PMC4127755          DOI: 10.1136/bcr-2013-200958

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  3 in total

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Journal:  Clin Toxicol (Phila)       Date:  2005       Impact factor: 4.467

2.  Severe hepatotoxicity by Indian Ayurvedic herbal products: a structured causality assessment.

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Journal:  Ann Hepatol       Date:  2009 Jul-Sep       Impact factor: 2.400

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Authors:  M Kesavan; K S Mohan; K Rajagopalan; R Kuttan
Journal:  Anc Sci Life       Date:  1990-04
  3 in total
  3 in total

Review 1.  The Safety of Medicinal Plants Used in the Treatment of Vitiligo and Hypermelanosis: A Systematic Review of Use and Reports of Harm.

Authors:  Irshad Hussain
Journal:  Clin Cosmet Investig Dermatol       Date:  2021-03-23

2.  Psoralen Induced Liver Injury by Attenuating Liver Regenerative Capability.

Authors:  Wang Zhou; Xi Chen; Guolin Zhao; Dengqiu Xu; Zhenzhou Jiang; Luyong Zhang; Tao Wang
Journal:  Front Pharmacol       Date:  2018-10-22       Impact factor: 5.810

3.  Five Constituents Contributed to the Psoraleae Fructus-Induced Hepatotoxicity via Mitochondrial Dysfunction and Apoptosis.

Authors:  Zhaojuan Guo; Pin Li; Chunguo Wang; Qianjun Kang; Can Tu; Bingqian Jiang; Jingxuan Zhang; Weiling Wang; Ting Wang
Journal:  Front Pharmacol       Date:  2021-12-07       Impact factor: 5.810

  3 in total

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