Literature DB >> 25102674

[Primary ovarian carcinosarcoma. Report of eight cases].

Gonzalo Montalvo-Esquivel, José Gregorio Chanona-Vilchis, Angel Herrera-Gómez, Antelmo Abelardo Meneses-García, David Isla-Ortiz.   

Abstract

BACKGROUND: The carcinosarcoma, or Mixed Mullerian Malign Tumors, represent 1% of malignant ovarian neoplasm, they are formed by a component epithelium and another mesenquimal malignant both.
OBJECTIVE: Report the experience of the Ginecological Department of the Instituto Nacional de Cancerología (Mexico) in the treatment of patients with ovarian carcinosarcoma or primary malignant of the ovary.
METHODS: A retrospective of 8 cases of carcinosarcoma primary of ovary at National Institute of Cancerology, from January, 2005 to December, 2008.
RESULTS: The carcinosarcoma or Mixed Mullerian Malign Tumors appeared in 4.1% of all the malignant primary tumors of ovary, the clinical initial presentation was with pain and abdominal expansion both in 62.5% and mass palpable and bled vaginal in 25% of the patients. In 2/8 (25%) patients there was achieved a residual tumor minor of 1cm, in 4/8 (50%) cases one administered chemotherapy. In 3/8 (37.5%) they were kept free of disease in the follow-up of 42 months, 1/8 (12.5%) with stable disease and 4/8 (50%) they died for disease.
CONCLUSIONS: Ovarian carcinosarcoma is a rare tumor, the clinical of this neoplasm is aggressive, usually presenting in advanced stages, with a poor prognosis with existing medical treatment.

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Year:  2014        PMID: 25102674

Source DB:  PubMed          Journal:  Ginecol Obstet Mex        ISSN: 0300-9041


  2 in total

1.  Genetic Analysis and Combined Therapy of Surgery and Chemotherapy for the Progression-Free Survival of a Patient with Ovarian Carcinosarcoma: A Case Report and Literature Review.

Authors:  Shanshan Guo; Xiaoyun Zhang; Qianjue Tang; Mengyun Zhou; Dan Jiang; Erkai Yu
Journal:  Onco Targets Ther       Date:  2022-06-29       Impact factor: 4.345

2.  Multiple pulmonary metastases with halo-sign from malignant mixed Müllerian tumors.

Authors:  Hong-Wei Tian; Wei-Bing Yang; Meng-Jie Yang; Jing-Yuan Liu; Jian-Chu Zhang; Xiao-Nan Tao; Qiong Zhou
Journal:  Oncol Lett       Date:  2017-09-22       Impact factor: 2.967

  2 in total

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