Literature DB >> 25100824

Serum neutralization assay can efficiently replace plaque reduction neutralization test for detection and quantitation of West Nile virus antibodies in human and animal serum samples.

Annapia Di Gennaro1, Alessio Lorusso2, Claudia Casaccia1, Annamaria Conte1, Federica Monaco1, Giovanni Savini1.   

Abstract

A serum neutralization assay (SN) was compared with the official plaque reduction neutralization test for the quantitation of West Nile virus antibodies. A total of 1,348 samples from equid sera and 38 from human sera were tested by these two methods. Statistically significant differences were not observed, thus supporting the use of SN for routine purposes.
Copyright © 2014, American Society for Microbiology. All Rights Reserved.

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Year:  2014        PMID： 25100824      PMCID： PMC4266345          DOI： 10.1128/CVI.00426-14

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


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