Literature DB >> 25099680

Heterotopic gastric mucosa of the proximal oesophagus (inlet patch): endoscopic prevalence, histological and clinical characteristics in paediatric patients.

Alejandro Rodríguez-Martínez1, José C Salazar-Quero, Carlos Tutau-Gómez, Beatriz Espín-Jaime, María Rubio-Murillo, Antonia Pizarro-Martín.   

Abstract

BACKGROUND: Heterotopic gastric mucosa is found in the proximal oesophagus, just below the upper oesophageal sphincter, and is encountered when the oesophagus is examined carefully during endoscopy. AIMS: In this study on paediatric patients, we aimed to determine the endoscopic prevalence of heterotopic gastric mucosa of the proximal oesophagus (HGMPO), to identify its macroscopic and histological characteristics and to evaluate its clinical features. PATIENTS AND METHODS: A total of 1399 patients were examined. Ages, sex, clinical and endoscopic findings of all patients were recorded. Patients with HGMPO were classified in accordance with a clinicopathological classification and information on the treatment and evolution was also recorded.
RESULTS: Of the 1399 patients, 20 (11 male) were found to have HGMPO. The prevalence of HGMPO was determined to be 1.4%. In five patients, the upper oesophageal and laryngopharyngeal symptoms were remarkable. The clinicopathological classification showed that 15 patients were HGMPO type 1 (asymptomatic) and five were type 2 (symptomatic without morphologic changes). There was no significant association of any other endoscopic finding with the presence of an HGMPO. Proton pump inhibitors treatment was initiated in 16 patients, including those with HGMPO type 2. In one type 2 patient who showed no improvement during medical treatment, endoscopic treatment was indicated (argon plasma ablation). In patients with symptoms attributable to the presence of the inlet patch, the proposed treatment resolved clinical symptoms.
CONCLUSION: The presence of HGMPO is not an infrequent finding in thorough endoscopies. Although HGMPO does not usually have a symptomatic progression, it can sometimes lead to supraoesophageal symptoms; thus, treatment should be considered.

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Year:  2014        PMID: 25099680     DOI: 10.1097/MEG.0000000000000177

Source DB:  PubMed          Journal:  Eur J Gastroenterol Hepatol        ISSN: 0954-691X            Impact factor:   2.566


  7 in total

1.  Endoscopic Mucosectomy in a Child Presenting with Gastric Heterotopia of the Rectum.

Authors:  Joana Soares; Carla Ferreira; Margarida Marques; Susana Corujeira; Marta Tavares; Joanne Lopes; Fátima Carneiro; Jorge Amil Dias; Eunice Trindade
Journal:  GE Port J Gastroenterol       Date:  2017-09-02

Review 2.  Heterotopic gastric mucosa in the anus and rectum: first case report of endoscopic submucosal dissection and systematic review.

Authors:  Federico Iacopini; Takuji Gotoda; Walter Elisei; Patrizia Rigato; Fabrizio Montagnese; Yutaka Saito; Guido Costamagna; Giampaolo Iacopini
Journal:  Gastroenterol Rep (Oxf)       Date:  2016-04-21

3.  Gastric adenocarinoma of the upper oesophagus: A literature review and case report.

Authors:  Georgina E Riddiough; Steve T Hornby; Khashayar Asadi; Ahmed Aly
Journal:  Int J Surg Case Rep       Date:  2016-12-01

4.  The prevalence of gastric heterotopia of the proximal esophagus is underestimated, but preneoplasia is rare - correlation with Barrett's esophagus.

Authors:  Ulrich Peitz; Michael Vieth; Matthias Evert; Jovana Arand; Albert Roessner; Peter Malfertheiner
Journal:  BMC Gastroenterol       Date:  2017-07-12       Impact factor: 3.067

5.  Gastric heterotopia in rectum: A literature review and its diagnostic pitfall.

Authors:  Peyman Dinarvand; Ashley A Vareedayah; Nancy J Phillips; Christine Hachem; Jinping Lai
Journal:  SAGE Open Med Case Rep       Date:  2017-02-17

Review 6.  Issues and controversies in esophageal inlet patch.

Authors:  Adriana Ciocalteu; Petrica Popa; Mircea Ionescu; Dan Ionut Gheonea
Journal:  World J Gastroenterol       Date:  2019-08-14       Impact factor: 5.742

7.  Adenocarcinoma Arising From a Cervical Esophageal Inlet Patch: The Malignant Potential of a Small Lesion.

Authors:  Karolina N Dziadkowiec; Sergio A Sánchez-Luna; Peter Stawinski; Jose Proenza
Journal:  Cureus       Date:  2020-07-19
  7 in total

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