Literature DB >> 25099635

Predictive factors for return of erectile function in robotic radical prostatectomy: case series from a single centre.

F J Garcia1, P D Violette1, G B Brock2, S E Pautler2.   

Abstract

Postprostatectomy erectile dysfunction is a frequent complication of robotic-assisted radical prostatectomy (RARP). We attempted to retrospectively identify objective predictors of erectile recovery in a population of potent men undergoing RARP. Data for 375 consecutive patients were collected prospectively from a single surgeon in an academic institution from 2005 to 2011. Inclusion criteria were 2 years of complete follow-up, preoperative International Index of Erectile Function (IIEF) scores of ≥ 22 without erectogenic aids and no adjuvant therapy (n = 86). Patients were grouped by erectile function at 2 years as 'Recovery' (IIEF ≥ 17, n = 41) and 'non-recovery' (IIEF < 16, n = 45). Baseline and perioperative characteristics were evaluated between groups. Body mass index, operative time and gland volumes were not different between groups. Univariate analysis demonstrated that higher preoperative prostate-specific antigen, longer apical dissection time and non-nerve-sparing surgery decreased erectile recovery. Multivariable analysis demonstrated that longer apical dissection time remained an independent predictor of decreased erectile function (P < 0.001). In contrast, postoperative intracavernosal injection (ICI) was found to predict erectile recovery (P = 0.017). At 2-year follow-up, prolonged apical dissection time predicts nonrecovery and ICI rehabilitation predicts recovery of erectile function after RARP. This can inform patients' postoperative expectations. However, further studies are needed to support the findings of this exploratory analysis.

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Year:  2014        PMID: 25099635     DOI: 10.1038/ijir.2014.20

Source DB:  PubMed          Journal:  Int J Impot Res        ISSN: 0955-9930            Impact factor:   2.896


  31 in total

Review 1.  Systematic review and meta-analysis of studies reporting potency rates after robot-assisted radical prostatectomy.

Authors:  Vincenzo Ficarra; Giacomo Novara; Thomas E Ahlering; Anthony Costello; James A Eastham; Markus Graefen; Giorgio Guazzoni; Mani Menon; Alexandre Mottrie; Vipul R Patel; Henk Van der Poel; Raymond C Rosen; Ashutosh K Tewari; Timothy G Wilson; Filiberto Zattoni; Francesco Montorsi
Journal:  Eur Urol       Date:  2012-06-01       Impact factor: 20.096

Review 2.  Retropubic, laparoscopic, and robot-assisted radical prostatectomy: a systematic review and cumulative analysis of comparative studies.

Authors:  Vincenzo Ficarra; Giacomo Novara; Walter Artibani; Andrea Cestari; Antonio Galfano; Markus Graefen; Giorgio Guazzoni; Bertrand Guillonneau; Mani Menon; Francesco Montorsi; Vipul Patel; Jens Rassweiler; Hendrik Van Poppel
Journal:  Eur Urol       Date:  2009-01-25       Impact factor: 20.096

3.  Reporting the Canadian robotic experience: The outcomes and how we report them.

Authors:  Stephen E Pautler
Journal:  Can Urol Assoc J       Date:  2013 Sep-Oct       Impact factor: 1.862

Review 4.  Systematic review of methods for reporting combined outcomes after radical prostatectomy and proposal of a novel system: the survival, continence, and potency (SCP) classification.

Authors:  Vincenzo Ficarra; Prasanna Sooriakumaran; Giacomo Novara; Oscar Schatloff; Alberto Briganti; Henk Van der Poel; Francesco Montorsi; Vip Patel; Ashutosh Tewari; Alexander Mottrie
Journal:  Eur Urol       Date:  2011-12-02       Impact factor: 20.096

Review 5.  Current state of penile rehabilitation after radical prostatectomy.

Authors:  Francisco Javier Garcia; Gerald Brock
Journal:  Curr Opin Urol       Date:  2010-05       Impact factor: 2.309

6.  Pentafecta: a new concept for reporting outcomes of robot-assisted laparoscopic radical prostatectomy.

Authors:  Vipul R Patel; Ananthakrishnan Sivaraman; Rafael F Coelho; Sanket Chauhan; Kenneth J Palmer; Marcelo A Orvieto; Ignacio Camacho; Geoff Coughlin; Bernardo Rocco
Journal:  Eur Urol       Date:  2011-01-25       Impact factor: 20.096

7.  Activated RhoA/Rho kinase impairs erectile function after cavernous nerve injury in rats.

Authors:  Christian Gratzke; Travis D Strong; Milena A Gebska; Hunter C Champion; Christian G Stief; Arthur L Burnett; Trinity J Bivalacqua
Journal:  J Urol       Date:  2010-09-18       Impact factor: 7.450

8.  Effect of prostate gland size on the learning curve for robot-assisted laparoscopic radical prostatectomy: does size matter initially?

Authors:  Carlos H Martínez; Venu Chalasani; Darwin Lim; Linda Nott; Reem J Al-Bareeq; Geoffrey R Wignall; Larry Stitt; Stephen E Pautler
Journal:  J Endourol       Date:  2010-02       Impact factor: 2.942

9.  Radical prostatectomy with preservation of sexual function: anatomical and pathological considerations.

Authors:  P C Walsh; H Lepor; J C Eggleston
Journal:  Prostate       Date:  1983       Impact factor: 4.104

Review 10.  Prevention and management of postprostatectomy sexual dysfunctions. Part 1: choosing the right patient at the right time for the right surgery.

Authors:  Andrea Salonia; Arthur L Burnett; Markus Graefen; Kostas Hatzimouratidis; Francesco Montorsi; John P Mulhall; Christian Stief
Journal:  Eur Urol       Date:  2012-05-03       Impact factor: 20.096

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  4 in total

1.  Penile rehabilitation for robotic radical prostatectomy: a new game.

Authors:  S S Goonewardene; R Persad; D Gillatt
Journal:  J Robot Surg       Date:  2015-12-24

2.  Factors predicting outcomes of penile rehabilitation with udenafil 50 mg following radical prostatectomy.

Authors:  T-H Kim; Y-S Ha; S H Choi; E S Yoo; B W Kim; S-J Yun; W-J Kim; Y S Kwon; T G Kwon
Journal:  Int J Impot Res       Date:  2015-10-29       Impact factor: 2.896

3.  Erectile dysfunction after sickle cell disease-associated recurrent ischemic priapism: profile and risk factors.

Authors:  Uzoma A Anele; Arthur L Burnett
Journal:  J Sex Med       Date:  2015-01-09       Impact factor: 3.802

4.  Association between masturbation and functional outcome in the postoperative course after nerve-sparing radical prostatectomy.

Authors:  Valentin H Meissner; Sonja Dumler; Martina Kron; Stefan Schiele; Veronika E Goethe; Andreas Bannowsky; Jürgen E Gschwend; Kathleen Herkommer
Journal:  Transl Androl Urol       Date:  2020-06
  4 in total

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