Literature DB >> 2509940

Rescue of bicoid mutant Drosophila embryos by bicoid fusion proteins containing heterologous activating sequences.

W Driever1, J Ma, C Nüsslein-Volhard, M Ptashne.   

Abstract

The maternal gene bicoid (bcd) determines pattern in the anterior half of the Drosophila embryo. It is reported here that the injection of bcd mutant embryos with messenger RNAs that encode proteins consisting of heterologous acidic transcriptional activating sequences fused to the DNA-binding portion of the bcd gene product, can completely restore the anterior pattern of the embryo.

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Year:  1989        PMID： 2509940     DOI： 10.1038/342149a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  34 in total

1.  Chip interacts with diverse homeodomain proteins and potentiates bicoid activity in vivo.

Authors:  E Torigoi; I M Bennani-Baiti; C Rosen; K Gonzalez; P Morcillo; M Ptashne; D Dorsett
Journal:  Proc Natl Acad Sci U S A       Date:  2000-03-14       Impact factor: 11.205

2.  Target selectivity of bicoid is dependent on nonconsensus site recognition and protein-protein interaction.

Authors:  C Zhao; V Dave; F Yang; T Scarborough; J Ma
Journal:  Mol Cell Biol       Date:  2000-11       Impact factor: 4.272

3.  A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity.

Authors:  N Silverman; R Zhou; S Stöven; N Pandey; D Hultmark; T Maniatis
Journal:  Genes Dev       Date:  2000-10-01       Impact factor: 11.361

4.  Bicoid associates with the 5'-cap-bound complex of caudal mRNA and represses translation.

Authors:  Dierk Niessing; Stephen Blanke; Herbert Jäckle
Journal:  Genes Dev       Date:  2002-10-01       Impact factor: 11.361

5.  Refined LexA transactivators and their use in combination with the Drosophila Gal4 system.

Authors:  Ryohei Yagi; Franz Mayer; Konrad Basler
Journal:  Proc Natl Acad Sci U S A       Date:  2010-08-30       Impact factor: 11.205

6.  Activating regions of yeast transcription factors must have both acidic and hydrophobic amino acids.

Authors:  D M Ruden
Journal:  Chromosoma       Date:  1992-03       Impact factor: 4.316

7.  Mapping functional regions of the segment-specific transcription factor Krox-20.

Authors:  C Vesque; P Charnay
Journal:  Nucleic Acids Res       Date:  1992-05-25       Impact factor: 16.971

Review 8.  Robust generation and decoding of morphogen gradients.

Authors:  Naama Barkai; Ben-Zion Shilo
Journal:  Cold Spring Harb Perspect Biol       Date:  2009-11       Impact factor: 10.005

9.  Distinguishing direct from indirect roles for bicoid mRNA localization factors.

Authors:  Timothy T Weil; Despina Xanthakis; Richard Parton; Ian Dobbie; Catherine Rabouille; Elizabeth R Gavis; Ilan Davis
Journal:  Development       Date:  2010-01       Impact factor: 6.868

10.  Functionality of the GAL4/UAS system in Tribolium requires the use of endogenous core promoters.

Authors:  Johannes B Schinko; Markus Weber; Ivana Viktorinova; Alexandros Kiupakis; Michalis Averof; Martin Klingler; Ernst A Wimmer; Gregor Bucher
Journal:  BMC Dev Biol       Date:  2010-05-19       Impact factor: 1.978
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