Literature DB >> 25098030

Prediction of abnormal postpartum glucose tolerance testing in mild gestational diabetes mellitus.

Hector Mendez-Figueroa, Joshua D Dahlke, Julie Daley, Vrishali V Lopes, Donald R Coustan.   

Abstract

OBJECTIVE: To describe the liikelihood of women with gestational diabetes mellitus (GDM)--who are at increased risk for developing overt diabetes--undergoing postpartum testing, and the patient characteristics associated with abnormal postpartum glucose tolerance testing (GTT) in mild GDM. STUDY
DESIGN: This was a retrospective chart review that included mild GDM patients, defined as those with fasting plasma glucose levels < 95 mg/dL on a 3-hour 100-g oral glucose tolerance test (OGTT). Patients who underwent postpartum testing were assessed and predictive factors for abnormal results evaluated.
RESULTS: Mild GDM was diagnosed in 414 (39.6%) women, 201 (48.6%) of whom completed a postpartum 2-hour 75-g OGTT. Abnormal testing was seen in 69 (34.3%), with diabetes in 6 (3%); those with abnormal testing had been diagnosed with GDM at an earlier gestational age, had higher 1-hour 50-g OGTT values, and were also more likely to require pharmacologic therapy. Combining several variables produced a predictive model with positive and negative predictive values of 50% and 84%, respectively.
CONCLUSION: Antenatal factors (alone or in combination) do not allow for prediction of abnormal postpartum OGTT results in mild GDM patients. Patients with mild GDM are at a slightly decreased postpartum risk of developing diabetes and prediabetes as compared to other patients with GDM.

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Year:  2014        PMID: 25098030

Source DB:  PubMed          Journal:  J Reprod Med        ISSN: 0024-7758            Impact factor:   0.142


  2 in total

Review 1.  Postpartum glucose intolerance: an updated overview.

Authors:  Ida Pastore; Eusebio Chiefari; Raffaella Vero; Antonio Brunetti
Journal:  Endocrine       Date:  2017-08-14       Impact factor: 3.633

2.  Maternal Race/Ethnicity and Postpartum Diabetes Screening: A Systematic Review and Meta-Analysis.

Authors:  Cynthia J Herrick; Ritika Puri; Rana Rahaman; Angela Hardi; Karyn Stewart; Graham A Colditz
Journal:  J Womens Health (Larchmt)       Date:  2020-02-19       Impact factor: 2.681

  2 in total

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