Literature DB >> 2509720

Swainsonine: a new antineoplastic immunomodulator.

S Mohla, M J Humphries, S L White, K Matsumoto, S A Newton, C C Sampson, D Bowen, K Olden.   

Abstract

Swainsonine, an indolizidine alkaloid with immunomodulatory activity, has been found to be effective in inhibiting metastatic dissemination and growth of primary tumors of both murine and human origins. The unique ability of swainsonine to exhibit antimetastatic, anti-proliferative, and immunomodulatory activity imparts this drug a promising future in cancer therapy.

Entities:  

Mesh:

Substances:

Year:  1989        PMID: 2509720      PMCID: PMC2571577     

Source DB:  PubMed          Journal:  J Natl Med Assoc        ISSN: 0027-9684            Impact factor:   1.798


  58 in total

1.  New structural characteristic of the large glycopeptides from transformed cells.

Authors:  S I Ogata; T Muramatsu; A Kobata
Journal:  Nature       Date:  1976-02-19       Impact factor: 49.962

2.  Influence of cultivation, trypsinization and aggregation on the transplantability of melanoma B16 cells.

Authors:  B Hagmar; K Norrby
Journal:  Int J Cancer       Date:  1973-05       Impact factor: 7.396

Review 3.  Surface glycoproteins of cells before and after transformation by oncogenic viruses.

Authors:  L Warren; J P Fuhrer; C A Buck
Journal:  Fed Proc       Date:  1973-01

Review 4.  Tumor cell surfaces: general alterations detected by agglutinins.

Authors:  A M Rapin; M M Burger
Journal:  Adv Cancer Res       Date:  1974       Impact factor: 6.242

5.  The effect of trypsin and neuraminidase on the circulation and organ distribution of tumor cells.

Authors:  B K Sinha; G J Goldenberg
Journal:  Cancer       Date:  1974-12       Impact factor: 6.860

6.  Biochemical parameters correlated with tumour cell implantation.

Authors:  H B Bosmann; G F Bieber; A E Brown; K R Case; D M Gersten; T W Kimmerer; A Lione
Journal:  Nature       Date:  1973 Dec 21-28       Impact factor: 49.962

7.  The relationship of embolic homogeneity, number, size and viability to the incidence of experimental metastasis.

Authors:  I J Fidler
Journal:  Eur J Cancer       Date:  1973-03       Impact factor: 9.162

8.  Cell surface glycolipids and glycoproteins in malignant transformation.

Authors:  G Yogeeswaran
Journal:  Adv Cancer Res       Date:  1983       Impact factor: 6.242

9.  The significance of hematogenous tumor cell clumps in the metastatic process.

Authors:  L A Liotta; M G Saidel; J Kleinerman
Journal:  Cancer Res       Date:  1976-03       Impact factor: 12.701

10.  Different patterns of lectin binding and cell surface sialylation detected on related high- and low-metastatic tumor lines.

Authors:  P Altevogt; M Fogel; R Cheingsong-Popov; J Dennis; P Robinson; V Schirrmacher
Journal:  Cancer Res       Date:  1983-11       Impact factor: 12.701

View more
  1 in total

Review 1.  Glycan Mimetics from Natural Products: New Therapeutic Opportunities for Neurodegenerative Disease.

Authors:  Wenyue Wang; Sandeep Gopal; Roger Pocock; Zhicheng Xiao
Journal:  Molecules       Date:  2019-12-16       Impact factor: 4.411

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.