| Literature DB >> 25096565 |
Thorbjørn Hermanrud1, Julie Hjortsø Janner, Ida Elisabeth Steffensen.
Abstract
Sarcoidosis is an ordinary systemic inflammatory disease that can affect many organs. It is characterized by development of non-necrotizing granulomas. It commonly affects lungs (80%) while hypercalcaemia is found in 5% and reflects an activation of T-cells within the granulomas that causes an overproduction of 1,25-dihydroxyvitamin D3. We describe a case where hypercalcaemia was the only symptom in a patient with extrapulmonary sarcoidosis, and the investigation was misled by different serologic findings though PET-CT showed fludeoxyglucose uptake in the biceps femoris muscles. The diagnosis was made after a biopsy.Entities:
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Year: 2014 PMID: 25096565
Source DB: PubMed Journal: Ugeskr Laeger ISSN: 0041-5782