Literature DB >> 25096565

[Hypercalcaemia can be the only initial symptom of sarcoidosis].

Thorbjørn Hermanrud1, Julie Hjortsø Janner, Ida Elisabeth Steffensen.   

Abstract

Sarcoidosis is an ordinary systemic inflammatory disease that can affect many organs. It is characterized by development of non-necrotizing granulomas. It commonly affects lungs (80%) while hypercalcaemia is found in 5% and reflects an activation of T-cells within the granulomas that causes an overproduction of 1,25-dihydroxyvitamin D3. We describe a case where hypercalcaemia was the only symptom in a patient with extrapulmonary sarcoidosis, and the investigation was misled by different serologic findings though PET-CT showed fludeoxyglucose uptake in the biceps femoris muscles. The diagnosis was made after a biopsy.

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Year:  2014        PMID: 25096565

Source DB:  PubMed          Journal:  Ugeskr Laeger        ISSN: 0041-5782


  1 in total

Review 1.  Life-Threatening Hypercalcemia Revealing Diffuse and Isolated Acute Sarcoid-Like Myositis: A New Entity? (A Case-Series).

Authors:  Arthur Mageau; Aude Rigolet; Khadija Benali; Maria Chauchard; Salima Ladjeroud; Isabelle Mahe; Thierry Maisonobe; Marie-Paule Chauveheid; Thomas Papo; Karim Sacre
Journal:  Medicine (Baltimore)       Date:  2016-03       Impact factor: 1.889

  1 in total

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