Literature DB >> 2509402

Imaging of rats with mammary cancer with two 2-deoxy-2-[18F]fluoro-D-hexoses.

R Paul1, K Aho, J Bergman, M Haaparanta, J Kulmala, A Reissell, O Solin.   

Abstract

Rats with mammary cancer were imaged by scintigraphy: 10 rats with 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) and 10 rats with [18F]F-D-galactose. The uptake of both tracers was similar in the tumors--the tumor-to-normal tissue ratio was 2.7 +/- 1.1 for [18F]FDG and 2.3 +/- 0.9 for [18F]FDGal at 120 min after injection. In addition to the tumors [18F]FDG accumulated in the brain, bladder and heart, [18F]FDGal in the brain, bladder and liver. [18F]FDGal may be useful for tumor imaging in man; further studies should be addressed to elucidate the mechanism of [18F]FDGal uptake into tumors.

Entities:  

Mesh:

Substances:

Year:  1989        PMID: 2509402     DOI: 10.1016/0883-2897(89)90054-8

Source DB:  PubMed          Journal:  Int J Rad Appl Instrum B        ISSN: 0883-2897


  2 in total

1.  The potential use of 2-[¹⁸F]fluoro-2-deoxy-D-galactose as a PET/CT tracer for detection of hepatocellular carcinoma.

Authors:  Michael Sørensen; Kim Frisch; Dirk Bender; Susanne Keiding
Journal:  Eur J Nucl Med Mol Imaging       Date:  2011-05-07       Impact factor: 9.236

2.  Nucleophilic radiosynthesis of 2-[18F]fluoro-2-deoxy-D-galactose from Talose triflate and biodistribution in a porcine model.

Authors:  Kim Frisch; Dirk Bender; Søren B Hansen; Susanne Keiding; Michael Sørensen
Journal:  Nucl Med Biol       Date:  2011-02-04       Impact factor: 2.408

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.