| Literature DB >> 25093936 |
Marten Reister1, Klaus Hoffmeier2, Nicolas Krezdorn3, Bjoern Rotter4, Chunguang Liang5, Stefan Rund6, Thomas Dandekar7, Ulrich Sonnenborn8, Tobias A Oelschlaeger9.
Abstract
Escherichia coli strain Nissle 1917 (EcN) is the active principle of a probiotic preparation (trade name Mutaflor(®)) used for the treatment of patients with intestinal diseases such as ulcerative colitis and diarrhea. It has GRAS (generally recognized as save) status and has been shown to be a therapeutically effective drug (Sonnenborn and Schulze, 2009). The complete genomic DNA sequence will help in identifying genes and their products which are essential for the strains probiotic nature. Genbank/EMBL/DDBJ accession number: CP007799 (chromosome).Entities:
Keywords: Escherichia coli Nissle 1917; Genome DNA sequence; Probiotic drug
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Year: 2014 PMID: 25093936 DOI: 10.1016/j.jbiotec.2014.07.442
Source DB: PubMed Journal: J Biotechnol ISSN: 0168-1656 Impact factor: 3.307