Literature DB >> 25092016

Do clinicians recommend aspirin to patients for primary prevention of cardiovascular disease?

Kevin Fiscella1, Paul C Winters, Michael Mendoza, Gary J Noronha, Carlos M Swanger, John D Bisognano, Robert J Fortuna.   

Abstract

BACKGROUND: The United States Preventive Services Task Force (USPSTF) released updated guidelines in 2009 recommending aspirin to prevent myocardial infarction among at-risk men and stroke among at-risk women.
OBJECTIVE: Our aim was to examine clinician aspirin recommendation among eligible persons based on cardiovascular risk scores and USPSTF cutoffs.
DESIGN: We used across-sectional analysis of a current nationally representative sample. PARTICIPANTS: Participants were aged 40 years and older, and in the National Health and Nutrition Examination Survey (NHANES) (2011-2012). MAIN MEASURES: We determined aspirin eligibility for cardiovascular disease (CVD) prevention for each participant based on reported and assessed cardiovascular risk factors. We assessed men's risk using a published coronary heart disease risk calculator based on Framingham equations, and used a similar calculator for stroke to assess risk for women. We applied the USPSTF risk cutoffs for sex and age that account for offsetting risk for gastrointestinal hemorrhage. We assessed clinician recommendation for aspirin based on participant report.
RESULTS: Among men 45-79 years and women 55-79 years, 87 % of men and 16 % of women were potentially eligible for primary CVD aspirin prevention. Clinician recommendation rates for aspirin among those eligible were low, 34 % for men and 42 % for women. Rates were highest among diabetics (63 %), those 65 to 79 years (52 %) or those in poor health (44 %). In contrast, aspirin recommendation rates were 76 % for CVD secondary prevention. After accounting for patient factors, particularly age, eligibility for aspirin prevention was not significantly associated with receiving a clinician's recommendation for aspirin (AOR 0.99 %; CI 0.7-1.4).
CONCLUSIONS: Despite an "A recommendation" from the USPSTF for aspirin for primary prevention of CVD, the majority of men and women potentially eligible for aspirin did not recall a clinical recommendation from their clinician.

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Year:  2015        PMID: 25092016      PMCID: PMC4314492          DOI: 10.1007/s11606-014-2985-8

Source DB:  PubMed          Journal:  J Gen Intern Med        ISSN: 0884-8734            Impact factor:   5.128


  41 in total

1.  2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.

Authors:  Neil J Stone; Jennifer G Robinson; Alice H Lichtenstein; C Noel Bairey Merz; Conrad B Blum; Robert H Eckel; Anne C Goldberg; David Gordon; Daniel Levy; Donald M Lloyd-Jones; Patrick McBride; J Sanford Schwartz; Susan T Shero; Sidney C Smith; Karol Watson; Peter W F Wilson
Journal:  J Am Coll Cardiol       Date:  2013-11-12       Impact factor: 24.094

2.  Aspirin use among U.S. adults: Behavioral Risk Factor Surveillance System.

Authors:  Umed A Ajani; Earl S Ford; Kurt J Greenland; Wayne H Giles; Ali H Mokdad
Journal:  Am J Prev Med       Date:  2006-01       Impact factor: 5.043

Review 3.  The effect of giving global coronary risk information to adults: a systematic review.

Authors:  Stacey L Sheridan; Anthony J Viera; Mori J Krantz; Christa L Ice; Lesley E Steinman; Karen E Peters; Laurie A Kopin; Danielle Lungelow
Journal:  Arch Intern Med       Date:  2010-02-08

4.  Aspirin for prevention of cardiovascular events in a general population screened for a low ankle brachial index: a randomized controlled trial.

Authors:  F Gerald R Fowkes; Jacqueline F Price; Marlene C W Stewart; Isabella Butcher; Gillian C Leng; Alistair C H Pell; Peter A G Sandercock; Keith A A Fox; Gordon D O Lowe; Gordon D Murray
Journal:  JAMA       Date:  2010-03-03       Impact factor: 56.272

5.  Physicians' attitudes and preventive care delivery: insights from the DOPC study.

Authors:  David Litaker; Susan A Flocke; Joseph P Frolkis; Kurt C Stange
Journal:  Prev Med       Date:  2005-05       Impact factor: 4.018

6.  Aspirin use among adults aged 40 and older in the United States: results of a national survey.

Authors:  Michael Pignone; George K Anderson; Katherine Binns; Hugh H Tilson; Steven M Weisman
Journal:  Am J Prev Med       Date:  2007-05       Impact factor: 5.043

7.  Aspirin for the prevention of cardiovascular disease: U.S. Preventive Services Task Force recommendation statement.

Authors: 
Journal:  Ann Intern Med       Date:  2009-03-17       Impact factor: 25.391

8.  Exceptional mortality prediction by risk scores from common laboratory tests.

Authors:  Benjamin D Horne; Heidi T May; Joseph B Muhlestein; Brianna S Ronnow; Donald L Lappé; Dale G Renlund; Abdallah G Kfoury; John F Carlquist; Patrick W Fisher; Robert R Pearson; Tami L Bair; Jeffrey L Anderson
Journal:  Am J Med       Date:  2009-06       Impact factor: 4.965

9.  Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials.

Authors:  Colin Baigent; Lisa Blackwell; Rory Collins; Jonathan Emberson; Jon Godwin; Richard Peto; Julie Buring; Charles Hennekens; Patricia Kearney; Tom Meade; Carlo Patrono; Maria Carla Roncaglioni; Alberto Zanchetti
Journal:  Lancet       Date:  2009-05-30       Impact factor: 79.321

Review 10.  Does the routine use of global coronary heart disease risk scores translate into clinical benefits or harms? A systematic review of the literature.

Authors:  Stacey L Sheridan; Eric Crespo
Journal:  BMC Health Serv Res       Date:  2008-03-20       Impact factor: 2.655

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  10 in total

1.  Aspirin for primary prevention: what's a clinician to do?

Authors:  Mitchell A Psotka; Kirsten E Fleischmann
Journal:  J Gen Intern Med       Date:  2015-02       Impact factor: 5.128

2.  Impact of updated recommendations on acetylsalicylic acid use for primary prevention of cardiovascular disease in Canada: a population-based survey.

Authors:  Myriam Khalili; Fanny Lepeytre; Jason Robert Guertin; Rémi Goupil; Stéphan Troyanov; Josée Bouchard; François Madore
Journal:  CMAJ Open       Date:  2020-01-28

3.  Priorities among effective clinical preventive services in British Columbia, Canada.

Authors:  Hans Krueger; Sylvia Robinson; Trevor Hancock; Richard Birtwhistle; Jane A Buxton; Bonnie Henry; Jennifer Scarr; John J Spinelli
Journal:  BMC Health Serv Res       Date:  2022-04-26       Impact factor: 2.908

4.  Preventive Aspirin and Other Antiplatelet Medication Use Among U.S. Adults Aged ≥ 40 Years: Data from the National Health and Nutrition Examination Survey, 2011-2012.

Authors:  Qiuping Gu; Charles F Dillon; Mark S Eberhardt; Jacqueline D Wright; Vicki L Burt
Journal:  Public Health Rep       Date:  2015 Nov-Dec       Impact factor: 2.792

5.  Aspirin Use and Misuse for the Primary Prevention of Cardiovascular Diseases.

Authors:  Russell V Luepker; Niki C Oldenburg; Jeffrey R Misialek; Jeremy R Van't Hof; John R Finnegan; Milton Eder; Sue Duval
Journal:  Am J Prev Med       Date:  2021-02-03       Impact factor: 5.043

6.  Use of Aspirin and Statin as primary prevention for cardiovascular diseases.

Authors:  Bahaa Aba Alkhail; Rahila Iftikhar; Adnan Al Shaikh
Journal:  Pak J Med Sci       Date:  2016 Nov-Dec       Impact factor: 1.088

7.  Aspirin prescribing pattern and guidelines-adherence evaluation for primary prevention of cardiovascular diseases at a teaching hospital.

Authors:  Salman Almalki; Abdulaziz Alhossan; Bashayer Alrumayyan; Khansa Alanazi; Saja Bane Gamea; Marwa Alesikri; Ajaz Ahmad; Ziyad Alrabiah
Journal:  Saudi Pharm J       Date:  2021-11-08       Impact factor: 4.330

8.  Cost-Effectiveness of a Statewide Campaign to Promote Aspirin Use for Primary Prevention of Cardiovascular Disease.

Authors:  Tzeyu L Michaud; Jean Abraham; Hawre Jalal; Russell V Luepker; Sue Duval; Alan T Hirsch
Journal:  J Am Heart Assoc       Date:  2015-12-23       Impact factor: 5.501

9.  Within-the-Clinic Shared Decision for an Over-the-Counter Medication.

Authors:  Ju H Kim; William B Borden
Journal:  J Am Heart Assoc       Date:  2015-12-23       Impact factor: 5.501

Review 10.  Aspirin for primary prevention of cardiovascular disease.

Authors:  Jobert Richie N Nansseu; Jean Jacques N Noubiap
Journal:  Thromb J       Date:  2015-12-04
  10 in total

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