Literature DB >> 25091744

Characterization of a novel highly pathogenic H5N2 avian influenza virus isolated from a duck in eastern China.

Haibo Wu1, Xiaorong Peng, Lihua Xu, Changzhong Jin, Linfang Cheng, Xiangyun Lu, Tiansheng Xie, Hangping Yao, Nanping Wu.   

Abstract

During surveillance for avian influenza viruses (AIVs) in live-poultry markets (LPMs) in eastern China in 2013, one H5N2 AIV was isolated from a duck. Phylogenetic analysis showed that the hemagglutinin of this strain belongs to clade 2.3.4 and received its genes from H5, H3 and H6 AIVs of poultry in China. The virulence of this strain was examined in chickens and mice, and it was found to be highly pathogenic in chickens but demonstrated moderate pathogenicity in mice. These results suggest that active surveillance of AIVs in LPMs should be used in an early warning system for avian influenza outbreaks.

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Year:  2014        PMID： 25091744     DOI： 10.1007/s00705-014-2193-1

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  8 in total

1.  Genetic characterization of natural reassortant H4 subtype avian influenza viruses isolated from domestic ducks in Zhejiang province in China from 2013 to 2014.

Authors:  Haibo Wu; Xiuming Peng; Xiaorong Peng; Linfang Cheng; Xiangyun Lu; Changzhong Jin; Tiansheng Xie; Hangping Yao; Nanping Wu
Journal:  Virus Genes       Date:  2015-09-09       Impact factor: 2.332

2.  Genomic and phylogenetic characterization of novel, recombinant H5N2 avian influenza virus strains isolated from vaccinated chickens with clinical symptoms in China.

Authors:  Huaiying Xu; Fang Meng; Dihai Huang; Xiaodan Sheng; Youling Wang; Wei Zhang; Weishan Chang; Leyi Wang; Zhuoming Qin
Journal:  Viruses       Date:  2015-02-25       Impact factor: 5.048

3.  Nomenclature updates resulting from the evolution of avian influenza A(H5) virus clades 2.1.3.2a, 2.2.1, and 2.3.4 during 2013-2014.

Authors:  Gavin J D Smith; Ruben O Donis
Journal:  Influenza Other Respir Viruses       Date:  2015-09       Impact factor: 4.380

4.  Novel H5 clade 2.3.4.6 viruses with both α-2,3 and α-2,6 receptor binding properties may pose a pandemic threat.

Authors:  Qunhui Li; Xuan Wang; Min Gu; Jie Zhu; Xiaoli Hao; Zhao Gao; Zhongtao Sun; Jiao Hu; Shunlin Hu; Xiaoquan Wang; Xiaowen Liu; Xiufan Liu
Journal:  Vet Res       Date:  2014-12-17       Impact factor: 3.683

5.  Genetic and molecular characterization of H9N2 and H5 avian influenza viruses from live poultry markets in Zhejiang Province, eastern China.

Authors:  Haibo Wu; Xiuming Peng; Xiaorong Peng; Linfang Cheng; Xiangyun Lu; Changzhong Jin; Tiansheng Xie; Hangping Yao; Nanping Wu
Journal:  Sci Rep       Date:  2015-12-02       Impact factor: 4.379

6.  Characterization of Novel Reassortant Influenza A (H5N2) Viruses Isolated from Poultry in Eastern China, 2015.

Authors:  Haibo Wu; Rufeng Lu; Xiuming Peng; Xiaorong Peng; Linfang Cheng; Fumin Liu; Nanping Wu
Journal:  Front Microbiol       Date:  2017-04-25       Impact factor: 5.640

7.  Genetic Characterization and Pathogenesis of Three Novel Reassortant H5N2 Viruses in South Korea, 2018.

Authors:  Anh Thi Viet Nguyen; Vui Thi Hoang; Haan Woo Sung; Seon-Ju Yeo; Hyun Park
Journal:  Viruses       Date:  2021-10-30       Impact factor: 5.048

8.  Amino acid substitutions involved in the adaptation of a novel highly pathogenic H5N2 avian influenza virus in mice.

Authors:  Haibo Wu; Xiuming Peng; Xiaorong Peng; Nanping Wu
Journal:  Virol J       Date:  2016-09-23       Impact factor: 4.099
  8 in total

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