Literature DB >> 25091728

Obesity: CPAP effects in sleep apnoea-what should be expected?

Patrick Lévy1, Jean-Louis Pépin1.   

Abstract

Patients with obesity and obstructive sleep apnoea have increased morbidity. Now, one study has reported limited beneficial effects of continuous positive airway pressure (CPAP) in patients with both these conditions. However, in another study, the reduction in blood pressure obtained with CPAP was not observed when nocturnal hypoxia was suppressed with supplemental oxygen.

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Year:  2014        PMID： 25091728     DOI： 10.1038/nrendo.2014.131

Source DB:  PubMed          Journal:  Nat Rev Endocrinol        ISSN： 1759-5029            Impact factor:   43.330


  10 in total

Review 1.  Sleep, sleep-disordered breathing and metabolic consequences.

Authors:  P Lévy; M R Bonsignore; J Eckel
Journal:  Eur Respir J       Date:  2009-07       Impact factor: 16.671

2.  Comparison of continuous positive airway pressure and valsartan in hypertensive patients with sleep apnea.

Authors:  Jean-Louis Pépin; Renaud Tamisier; Gilles Barone-Rochette; Sandrine H Launois; Patrick Lévy; Jean-Philippe Baguet
Journal:  Am J Respir Crit Care Med       Date:  2010-06-03       Impact factor: 21.405

3.  14 nights of intermittent hypoxia elevate daytime blood pressure and sympathetic activity in healthy humans.

Authors:  R Tamisier; J L Pépin; J Rémy; J P Baguet; J A Taylor; J W Weiss; P Lévy
Journal:  Eur Respir J       Date:  2010-06-04       Impact factor: 16.671

Review 4.  Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities.

Authors:  W T McNicholas; M R Bonsigore; M R Bonsignore
Journal:  Eur Respir J       Date:  2007-01       Impact factor: 16.671

5.  Chronic intermittent hypoxia is a major trigger for non-alcoholic fatty liver disease in morbid obese.

Authors:  Judith Aron-Wisnewsky; Caroline Minville; Joan Tordjman; Patrick Lévy; Jean-Luc Bouillot; Arnaud Basdevant; Pierre Bedossa; Karine Clément; Jean-Louis Pépin
Journal:  J Hepatol       Date:  2011-05-19       Impact factor: 25.083

6.  Serum urate levels are unchanged with continuous positive airway pressure therapy for obstructive sleep apnea: a randomized controlled trial.

Authors:  Benjamin Prudon; Edward Roddy; John R Stradling; Sophie D West
Journal:  Sleep Med       Date:  2013-09-20       Impact factor: 3.492

7.  Effects of continuous positive airway pressure on systemic inflammation in patients with moderate to severe obstructive sleep apnoea: a randomised controlled trial.

Authors:  M Kohler; L Ayers; J C T Pepperell; K L Packwood; B Ferry; N Crosthwaite; S Craig; M M Siccoli; R J O Davies; J R Stradling
Journal:  Thorax       Date:  2008-09-11       Impact factor: 9.139

8.  CPAP, weight loss, or both for obstructive sleep apnea.

Authors:  Julio A Chirinos; Indira Gurubhagavatula; Karen Teff; Daniel J Rader; Thomas A Wadden; Raymond Townsend; Gary D Foster; Greg Maislin; Hassam Saif; Preston Broderick; Jesse Chittams; Alexandra L Hanlon; Allan I Pack
Journal:  N Engl J Med       Date:  2014-06-12       Impact factor: 91.245

9.  CPAP versus oxygen in obstructive sleep apnea.

Authors:  Daniel J Gottlieb; Naresh M Punjabi; Reena Mehra; Sanjay R Patel; Stuart F Quan; Denise C Babineau; Russell P Tracy; Michael Rueschman; Roger S Blumenthal; Eldrin F Lewis; Deepak L Bhatt; Susan Redline
Journal:  N Engl J Med       Date:  2014-06-12       Impact factor: 91.245

10.  Continuous positive airway pressure improves sleepiness but not calculated vascular risk in patients with minimally symptomatic obstructive sleep apnoea: the MOSAIC randomised controlled trial.

Authors:  Sonya Elizabeth Craig; Malcolm Kohler; Debby Nicoll; Daniel J Bratton; Andrew Nunn; Robert Davies; John Stradling
Journal:  Thorax       Date:  2012-10-30       Impact factor: 9.139
  10 in total

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