| Literature DB >> 2509087 |
M Iinuma, T Tanaka, M Mizuno, T Katsuzaki, H Ogawa.
Abstract
To clarify the structure-activity correlation of flavonoids for inhibition of aldose reductase, about fifty flavonoid compounds were screened. The presence of hydrophobic substituents on the A ring and hydrophilic substituents on the B ring of the flavonoid skeleton was suggested to improve the potency of inhibitory activity. The activities of extracts of Scutellaria baicalensis, Andrographis paniculata and Gutierrezia microcephala are also described.Entities:
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Year: 1989 PMID： 2509087 DOI： 10.1248/cpb.37.1813
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645