Literature DB >> 25090743

[Diabetes mellitus and early failures in oral implantology].

P Niang, A Ba, Tine S Dia, B Tamba, Barry B C Gassama, B Diallo.   

Abstract

It has become increasingly common for diabetic patients to be considered as candidates for dental implants. However even though success rates of implant therapy in diabetic are high, this does not preclude failures. Failure to osseointegrate in the initial healing phase results in a fibrous tissue encapsulation of the implant and clinical mobility, leading ultimately to the failure of the implant. This review presents the current knowledge regarding the effect of diabetes mellitus on the osseointegration of implants including pathophysiologic aspects as well as their potential implications on bone metabolism and osseointegration, implant success rate at the second-phase surgery and guidelines for pre and post-operative management. In experimental models of diabetes mellitus, a reduced level of bone-implant contact has been shown, and this can be reversed by means of treatment with insulin. Compared with the general population, a higher failure rate is seen in diabetic patients. Most of these occur at the second-phase surgery, seemingly pointing to the microvascular complications of this condition as a possible causal factor. It is necessary to take certain special considerations into account for the placement of implants in diabetic patient. A good control of plasma glycemia, together with other measures, has been shown to improve the percentages of implant survival in these patients.

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Year:  2011        PMID: 25090743

Source DB:  PubMed          Journal:  Odontostomatol Trop        ISSN: 0251-172X


  2 in total

1.  Construction and performance of exendin-4-loaded chitosan-PLGA microspheres for enhancing implant osseointegration in type 2 diabetic rats.

Authors:  Shaojie Shi; Shuang Song; Xiangdong Liu; Guoqiang Zhao; Feng Ding; Wenshuang Zhao; Sijia Zhang; Yingliang Song; Wei Ma
Journal:  Drug Deliv       Date:  2022-12       Impact factor: 6.419

2.  Bone Marrow Mesenchymal Stromal Cells (BMMSCs) Augment Osteointegration of Dental Implants in Type 1 Diabetic Rabbits: An X-Ray Micro-Computed Tomographic Evaluation.

Authors:  Nabeeh Abdullah Alqahtani; Harish C Chandramoorthy; Sharaz Shaik; Jamaluddin Syed; Ramesh Chowdhary; Leoney Antony
Journal:  Medicina (Kaunas)       Date:  2020-03-25       Impact factor: 2.430

  2 in total

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