Literature DB >> 2509

The alternate complement pathway in inflammatory bowel disease. Quantitation of the C3 proactivator (factor B) protein.

P A Feinstein, S R Kaplan, W R Thayer.   

Abstract

A component of the complement system's alternate pathway was investigated in ulcerative colitis and Crohn's disease. The mean C3PA (Factor B) titer in normals was 74 +/- 15%; in ulcerative colitis, 92 +/- 18%; and in Crohn's disease, 119+/- 24%. Significance was at the P less than 0.001 level when the mean values for the ulcerative colitis and the Crohn's disease groups were compared to normal subjects. Titers did not change significantly with exacerbation or amelioration of the diseases or when patient groups were analyzed according to the mode of treatment received.

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Year:  1976        PMID： 2509

Source DB:  PubMed          Journal:  Gastroenterology        ISSN： 0016-5085            Impact factor:   22.682


  7 in total

1.  Defective release of C5a related chemo-attractant activity from complement in Crohn's disease.

Authors:  J Elmgreen; A Berkowicz; H Sørensen
Journal:  Gut       Date:  1983-06       Impact factor: 23.059

2.  Complement inhibitors and immunoconglutinins in ulcerative colitis and Crohn's disease.

Authors:  B J Potter; D J Brown; A Watson; D P Jewell
Journal:  Gut       Date:  1980-12       Impact factor: 23.059

3.  The complement profile in relation to the "reactor" state: a study in the immediate post-partum period.

Authors:  L W Mak
Journal:  Clin Exp Immunol       Date:  1978-03       Impact factor: 4.330

4.  Humoral immune system in inflammatory bowel disease: I. Complement levels.

Authors:  H J Hodgson; B J Potter; D P Jewell
Journal:  Gut       Date:  1977-09       Impact factor: 23.059

5.  Significance of serum complement levels in patients with gastrointestinal disease.

Authors:  I N Ross; R A Thompson; R D Montgomery; P Asquith
Journal:  J Clin Pathol       Date:  1979-08       Impact factor: 3.411

6.  [The immune competence of patients with Crohn's disease (author's transl)].

Authors:  E Tönnesmann; P A Bürkle; B Schäfer; K Federlin
Journal:  Klin Wochenschr       Date:  1979-10-15

7.  Retinal drusen counts are increased in inflammatory bowel disease, and with longer disease duration, more complications and associated IgA glomerulonephritis.

Authors:  E Nicklason; Y Ham; D Ng; S Glance; K Abel; P Harraka; H Mack; D Colville; J Savige
Journal:  Sci Rep       Date:  2022-07-11       Impact factor: 4.996
  7 in total

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