2-(1,2,3-Triazol-4-yl)pyridine-containing ethynylarenes as selective 'turn-on' fluorescent chemosensors for Ni(II).

A series of ethynylarene compounds containing 2-(1,2,3-triazol-4-yl)pyridine chelating units were studied as fluorescent chemosensors for metal cations in aqueous solution. Analogs possessing two chelating units bridged by either 1,4-diethynylphenyl or 2,7-diethynylnaphthyl subunits displayed large hypsochromic shifts coupled with signal intensification when exposed to increasing concentrations of Ni(II), a unique response among 22 metal cation analytes. This response was shown to be reversible, and is proposed to derive from disruption of aggregate formation upon Ni(II) binding at the peripheral chelating units.