Literature DB >> 25088397

Characterization, antibacterial, antioxidant, and cytotoxic activities of ZnO nanoparticles using Coptidis Rhizoma.

P C Nagajyothi1, T V M Sreekanth2, Clement O Tettey1, Yang In Jun1, Shin Heung Mook3.   

Abstract

Here, we report a simple, eco-friendly and inexpensive approach for the synthesis of zinc oxide nanoparticles (ZnO NPs) using Coptidis Rhizoma. The ZnO NPs were characterized by UV-visible absorption spectroscopy, FTIR, SEM-EDX, TGA, TEM, SAED and XRD. TEM images confirmed the presence of spherical and rod shaped ZnO NPs in the range of 2.90-25.20 nm. Green synthesized ZnO NPS exhibited moderate antibacterial activity against Gram-positive and Gram-negative bacteria and excellent DPPH free radical scavenging activity. Synthesized ZnO NPs had no toxic effects on the RAW 264.7 cell line.
Copyright © 2014. Published by Elsevier Ltd.

Entities:  

Keywords:  Antibacterial; Antioxidant; Coptidis Rhizoma; Cytotoxic activity; Green synthesis

Mesh：

Substances：

Year:  2014        PMID： 25088397     DOI： 10.1016/j.bmcl.2014.07.023

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  20 in total

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