Literature DB >> 25087616

Review of the botanical characteristics, phytochemistry, and pharmacology of Astragalus membranaceus (Huangqi).

Juan Fu1, Zenghui Wang, Linfang Huang, Sihao Zheng, Dongmei Wang, Shilin Chen, Haitao Zhang, Shihai Yang.   

Abstract

Astragalus membranaceus is one of the most widely used traditional Chinese herbal medicines. It is used as immune stimulant, tonic, antioxidant, hepatoprotectant, diuretic, antidiabetic, anticancer, and expectorant. The current paper reviews the botanical characteristics, phytochemistry, and pharmacology of Astragali Radix. Information on Astragali Radix was gathered via the Internet (using Google Scholar, Baidu Scholar, Elsevier, ACS, Medline Plus, CNKI, and Web of Science) as well as from libraries and local books. More than 100 compounds, including flavonoids, saponins, polysaccharides, and amino acids, have so far been identified, and the various biological activities of the compounds have been reported. As an important traditional Chinese medicine, further studies on Astragali Radix can lead to the development of new drugs and therapies for various diseases. The improvement of its utilization should be studied further.
Copyright © 2014 John Wiley & Sons, Ltd.

Entities:  

Keywords:  Astragalus membranaceus; biological activity; botanical characteristics

Mesh:

Substances:

Year:  2014        PMID: 25087616     DOI: 10.1002/ptr.5188

Source DB:  PubMed          Journal:  Phytother Res        ISSN: 0951-418X            Impact factor:   5.878


  124 in total

Review 1.  Drug Metabolism by the Host and Gut Microbiota: A Partnership or Rivalry?

Authors:  Hollie I Swanson
Journal:  Drug Metab Dispos       Date:  2015-08-10       Impact factor: 3.922

2.  Astragalus polysaccharide attenuates lipopolysaccharide-induced inflammatory responses in microglial cells: regulation of protein kinase B and nuclear factor-κB signaling.

Authors:  Tao Luo; Jian Qin; Min Liu; Jun Luo; Fang Ding; Mingling Wang; Limin Zheng
Journal:  Inflamm Res       Date:  2015-02-11       Impact factor: 4.575

3.  Astragalus polysaccharide suppresses palmitate-induced apoptosis in human cardiac myocytes: the role of Nrf1 and antioxidant response.

Authors:  Ji Zhang; Jian-Yun Gu; Zhi-Song Chen; Kai-Chen Xing; Bing Sun
Journal:  Int J Clin Exp Pathol       Date:  2015-03-01

4.  Occurrence of ochratoxin A in Astragalus propinquus root and its transfer to decoction.

Authors:  Jakub Toman; Vladimir Ostry; Yann Grosse; Tomas Roubal; Frantisek Malir
Journal:  Mycotoxin Res       Date:  2018-04-25       Impact factor: 3.833

5.  Pharmacokinetics Comparison, Intestinal Absorption and Acute Toxicity Assessment of a Novel Water-Soluble Astragaloside IV Derivative (Astragalosidic Acid, LS-102).

Authors:  Lin-Sen Qing; Ting-Bo Chen; Wen-Xia Sun; Li Chen; Pei Luo; Zhi-Feng Zhang; Li-Sheng Ding
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2019-04       Impact factor: 2.441

Review 6.  Antidiabetic Potential of Medicinal Plants and Their Active Components.

Authors:  Bahare Salehi; Athar Ata; Nanjangud V Anil Kumar; Farukh Sharopov; Karina Ramírez-Alarcón; Ana Ruiz-Ortega; Seyed Abdulmajid Ayatollahi; Patrick Valere Tsouh Fokou; Farzad Kobarfard; Zainul Amiruddin Zakaria; Marcello Iriti; Yasaman Taheri; Miquel Martorell; Antoni Sureda; William N Setzer; Alessandra Durazzo; Massimo Lucarini; Antonello Santini; Raffaele Capasso; Elise Adrian Ostrander; Muhammad Iqbal Choudhary; William C Cho; Javad Sharifi-Rad
Journal:  Biomolecules       Date:  2019-09-30

7.  Effects of fermented Chinese herbal medicines on milk performance and immune function in late-lactation cows under heat stress conditions.

Authors:  Chun-Hua Shan; Jianjun Guo; Xinsheng Sun; Nan Li; Xinyu Yang; Yuhong Gao; Dianrui Qiu; Xuemei Li; Yanan Wang; Man Feng; Chao Wang; Juan Juan Zhao
Journal:  J Anim Sci       Date:  2018-09-29       Impact factor: 3.159

Review 8.  Probiotics, fibre and herbal medicinal products for functional and inflammatory bowel disorders.

Authors:  Diego Currò; Gianluca Ianiro; Silvia Pecere; Stefano Bibbò; Giovanni Cammarota
Journal:  Br J Pharmacol       Date:  2016-10-25       Impact factor: 8.739

Review 9.  A systematic review of anticancer effects of radix astragali.

Authors:  Yeehong Jung; Uimin Jerng; Sookyung Lee
Journal:  Chin J Integr Med       Date:  2015-12-07       Impact factor: 1.978

10.  Screening and Identification of the Metabolites of Water Extracts of Raw and Honey-Processed Astragalus in Rat Urine Based on UHPLC/ESI-Q-TOF-MS and Multivariate Statistical Analysis.

Authors:  Jing Huang; Hongyuan Chen; Chanyi Li; Wuping Liu; Wenjie Ma; Wen Rui
Journal:  J Am Soc Mass Spectrom       Date:  2018-06-21       Impact factor: 3.109

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