Sophie Bucher1, Bernard Bauduceau2, Linda Benattar-Zibi3, Philippe Bertin4, Gilles Berrut5, Emmanuelle Corruble6, Nicolas Danchin7, Tiba Delespierre8, Geneviève Derumeaux9, Jean Doucet10, Bruno Falissard11, Francoise Forette12, Olivier Hanon13, Rissane Ourabah14, Florence Pasquier15, Celine Piedvache8, Michel Pinget16, Virginie Ringa17, Laurent Becquemont8. 1. General Practice Department, Paris-Sud Faculty of Medicine, University of Paris-Sud, Le Kremlin-Bicêtre, France; INSERM, CESP Centre for Research in Epidemiology and Population Health, U1018, Gender, Sexual and Reproductive Health Team, University of Paris-Sud, Le Kremlin-Bicêtre, France. Electronic address: sophie.bucher@u-psud.fr. 2. Endocrinology Department, Begin Hospital, Saint Mandé, France. 3. Medical Director of ORPEA/CLINEA, Puteaux, France. 4. Rheumatology Department, Limoges University Hospital, Limoges, France. 5. Clinical Gerontology, Nantes University Hospital, France. 6. INSERM U 669, Paris-Sud Faculty of Medicine, University of Paris-Sud, Psychiatry Department, Bicêtre University Hospital, Assistance Publique-Hôpitaux de Paris, Le Kremlin-Bicêtre, France. 7. HEGP, Coronary Diseases, Paris, France. 8. Pharmacology Department, Paris-Sud Faculty of Medicine, University of Paris-Sud, Assistance Publique-Hôpitaux de Paris, Bicêtre Hospital, Le Kremlin-Bicêtre, France. 9. Cardiovascular Functional Exploration, Louis Pradel Hospital, Hospices Civils de Lyon, Bron, France. 10. Internal Medicine, Geriatry and Therapeutics, Saint Julien University Hospital, Rouen University, Rouen, France. 11. INSERM U 669, Paris-Sud Faculty of Medicine, University of Paris-Sud, Biostatistics Department, Assistance Publique-Hôpitaux de Paris, Paul Brousse Hospital, Le Kremlin-Bicêtre, France. 12. University of Paris Descartes, National Foundation of Gerontology, Paris, France. 13. University of Paris Descartes, EA 4468, AP-HP, Broca Hospital, Geriatrics Department, Paris, France. 14. General Practice Department, Paris-Sud Faculty of Medicine, University of Paris-Sud, Le Kremlin-Bicêtre, France. 15. University of Lille Nord de France, UDSL, EA 1046, CHU, Lille, France. 16. Endocrinology, Diabetes and Nutrition-Related Diseases (NUDE Unit), Strasbourg University Hospital and the European Centre for the Study of Diabetes (CeeD), University of Strasbourg, Strasbourg, France. 17. INSERM, CESP Centre for Research in Epidemiology and Population Health, U1018, Gender, Sexual and Reproductive Health Team, University of Paris-Sud, Le Kremlin-Bicêtre, France.
Abstract
AIM: S.AGES is a multicenter prospective cohort study of non-institutionalized patients aged 65 and over with atrial fibrillation, type 2 diabetes or chronic pain. Its objective is to describe the medical management in primary care. This article presents the baseline characteristics of subjects in the diabetes subcohort and compares the results to those from cohorts of older diabetic patients. METHODS: From April 2009 to June 2011, 983 patients were included in the diabetes subcohort by 213 primary care providers. Demographic data, geriatric parameters and the history, characteristics and treatment of the diabetes were recorded at baseline. RESULTS: The mean age was 76.7 ± 5.9 years. Most patients were living independently, with no cognitive impairment and in relatively good health. The duration of diabetes was 11.3 ± 8.7 years with average HbA1c of 6.9 ± 1.0%. 20% of patients had macrovascular disease, 33% renal failure, 14.6% ocular complication and 7.1% neuropathy. The first-line antidiabetic treatment was metformin (61.2%) and 18% of patients had used insulin. Treatment intensified with the worsening of diabetic symptoms. When compared to those from French and North American cohorts, the results showed increased complications and use of insulin with age, disease duration and severity. CONCLUSION: Due to the method of recruitment, S.AGES patients were generally healthy with well-controlled diabetes. However, the results were consistent with those from other cohorts. Three-year follow-up is expected to study the management of diabetic patients aged 65 and over in primary care.
AIM: S.AGES is a multicenter prospective cohort study of non-institutionalized patients aged 65 and over with atrial fibrillation, type 2 diabetes or chronic pain. Its objective is to describe the medical management in primary care. This article presents the baseline characteristics of subjects in the diabetes subcohort and compares the results to those from cohorts of older diabeticpatients. METHODS: From April 2009 to June 2011, 983 patients were included in the diabetes subcohort by 213 primary care providers. Demographic data, geriatric parameters and the history, characteristics and treatment of the diabetes were recorded at baseline. RESULTS: The mean age was 76.7 ± 5.9 years. Most patients were living independently, with no cognitive impairment and in relatively good health. The duration of diabetes was 11.3 ± 8.7 years with average HbA1c of 6.9 ± 1.0%. 20% of patients had macrovascular disease, 33% renal failure, 14.6% ocular complication and 7.1% neuropathy. The first-line antidiabetic treatment was metformin (61.2%) and 18% of patients had used insulin. Treatment intensified with the worsening of diabetic symptoms. When compared to those from French and North American cohorts, the results showed increased complications and use of insulin with age, disease duration and severity. CONCLUSION: Due to the method of recruitment, S.AGES patients were generally healthy with well-controlled diabetes. However, the results were consistent with those from other cohorts. Three-year follow-up is expected to study the management of diabeticpatients aged 65 and over in primary care.
Authors: Aline de Sousa Barbosa Freitas Pereira; Gerly Anne de Castro Brito; Maria Laura de Souza Lima; Arnóbio Antônio da Silva Júnior; Emanuell Dos Santos Silva; Adriana Augusto de Rezende; Raul Hernandes Bortolin; Maria Galvan; Flávia Q Pirih; Raimundo Fernandes de Araújo Júnior; Caroline Addison Carvalho Xavier de Medeiros; Gerlane Coelho Bernando Guerra; Aurigena Antunes de Araújo Journal: Int J Mol Sci Date: 2018-11-06 Impact factor: 5.923