Literature DB >> 25085949

Unusual sequelae of adult-onset dermatomyositis.

Mohammad Ebrahim Naffaa1, Rema Bishara2, Yolanda Braun-Moscovici3, Alexandra Balbir-Gurman3.   

Abstract

A 44-year-old woman diagnosed with dermatomyositis 5 years ago based on progressive proximal muscle weakness, elevated creatine kinase, typical findings on electromyography and muscle biopsy. Despite the treatment, in contrast to improvement in her muscle symptoms, the heliotrope rash of her eyelids persisted. After several years, the patient developed multiple limited skin retraction lesions with hyperpigmentation on both lower limbs. Palpation of these lesions revealed dry, cold and very firm skin on both thighs and calves, particularly in the distal areas. X-ray and ultrasound imaging of the calves showed multiple subcutaneous calcifications in the distal muscles. 2014 BMJ Publishing Group Ltd.

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Year:  2014        PMID: 25085949      PMCID: PMC4127753          DOI: 10.1136/bcr-2014-204521

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  6 in total

1.  Role of activated macrophage and inflammatory cytokines in the development of calcinosis in juvenile dermatomyositis.

Authors:  Masaki Shimizu; Kazuyuki Ueno; Sayaka Ishikawa; Yoshihito Kasahara; Akihiro Yachie
Journal:  Rheumatology (Oxford)       Date:  2013-11-04       Impact factor: 7.580

2.  Calcinosis cutis occurring in association with autoimmune connective tissue disease: the Mayo Clinic experience with 78 patients, 1996-2009.

Authors:  Samuel J Balin; David A Wetter; Louise K Andersen; Mark D P Davis
Journal:  Arch Dermatol       Date:  2011-12-19

3.  TNFalpha-308A allele in juvenile dermatomyositis: association with increased production of tumor necrosis factor alpha, disease duration, and pathologic calcifications.

Authors:  L M Pachman; M R Liotta-Davis; D K Hong; T R Kinsella; E P Mendez; J M Kinder; E H Chen
Journal:  Arthritis Rheum       Date:  2000-10

4.  Aggressive management of juvenile dermatomyositis results in improved outcome and decreased incidence of calcinosis.

Authors:  Rita E Fisler; Marilyn G Liang; Robert C Fuhlbrigge; Ali Yalcindag; Robert P Sundel
Journal:  J Am Acad Dermatol       Date:  2002-10       Impact factor: 11.527

5.  Therapy of calcinosis universalis complicating adult dermatomyositis.

Authors:  Georgina Terroso; Miguel Bernardes; Abelha Aleixo; Pedro Madureira; Romana Vieira; Alexandra Bernardo; Lúcia Costa
Journal:  Acta Reumatol Port       Date:  2013 Jan-Mar       Impact factor: 1.290

Review 6.  Adult and juvenile dermatomyositis: are the distinct clinical features explained by our current understanding of serological subgroups and pathogenic mechanisms?

Authors:  Sarah L Tansley; Neil J McHugh; Lucy R Wedderburn
Journal:  Arthritis Res Ther       Date:  2013-04-08       Impact factor: 5.156

  6 in total

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