| Literature DB >> 25085666 |
Bishr Aldabagh1, Jayne Joo, Siegrid S Yu.
Abstract
Merkel cell carcinoma is an aggressive neuroendocrine tumor with a high incidence of local recurrence, regional nodal and distant metastasis, and a high mortality rate. It has been linked to a polyomavirus in addition to immune suppression. Traditionally, treatment options have been limited to surgery and radiation therapy. Better understanding of the molecular pathways of infection and carcinogenesis has provided potential molecular targets and potential immunotherapies which are discussed in this review.Entities:
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Year: 2014 PMID： 25085666 DOI： 10.12788/j.sder.0084
Source DB: PubMed Journal: Semin Cutan Med Surg ISSN： 1085-5629