| Literature DB >> 25084507 |
Kenya Matsushita1, Yuta Sato2, Shinji Funamoto3, Jun-ichi Tamura4.
Abstract
Protected sulfate groups may be used as an alternative tool to provide sulfate esters at hydroxyl and amino groups, particularly on complex glycans. We examined 2,2,2-trichloroethoxysulfation at the mono-, di-, and trihydroxyl groups of saccharide moieties to show regioselective sulfation. We found some side reactions including inter- and intramolecular nucleophilic reactions with 2,2,2-trichloroethoxysulfates.Entities:
Keywords: 2,2,2-Trichloroethoxysulfate; Glycan synthesis; Intramolecular attack; Protected sulfate; Sulfated oligosaccharide
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Year: 2014 PMID： 25084507 DOI： 10.1016/j.carres.2014.05.012
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104