| Literature DB >> 25083514 |
Silvia Pieraccini1, Michael A Terzidis, Enrico J Baldassarri, Giovanna Fragneto, Paolo Mariani, Stefano Masiero, Chryssostomos Chatgilialoglu.
Abstract
The self-assembly of a lipophilic derivative of (5'S)-5',8-cyclo-2'-deoxyguanosine, a mutagenic product formed by hydroxyl radical attack against DNA, has been investigated. This derivative forms, with high fidelity, a dodecameric complex composed of three stacked G-quartets in the presence of strontium picrate. This is the first example of a fully-anti lipophilic G-quadruplex.Entities:
Mesh：
Substances：
Year: 2014 PMID： 25083514 DOI： 10.1039/c4cc04275a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222