Tiffany Nguyen1, Eleanor Hattery1, Vijay P Khatri1. 1. Department of Surgery, Division of Surgical Oncology, University of California, Davis Heath System, Sacramento, CA, USA.
Abstract
BACKGROUND: Radiofrequency ablation (RFA) use in breast cancer is a developing area of research. There have been a number of published studies over the last decade, which explores the feasibility of minimally invasive techniques in breast cancer treatment. In this review, we will discuss the most recent data on radiofrequency ablation and examine the current methods, outcomes, complications, and limitations of RFA in breast cancer therapy. METHODS: Pub Med search for English Language articles on RFA in breast cancer. RESULTS: More than 25 studies were reviewed and we searched for number of tumors, average size, electrode used, if they successfully ablated the tumor, when the tumor was then resected and if the patients experienced any complication from the ablation. CONCLUSIONS: Radiofrequency ablation is an emerging minimally invasive therapy in small, localized breast cancer. Currently, no clinical trials have been published to directly compare RFA to the current standard of surgical resection. Ultimately, RFA will need clinical trials to evaluate oncologic outcomes involving long interval follow-up to determine survival, local control and disease progression before it becomes a reasonable alternative to surgical resection.
BACKGROUND: Radiofrequency ablation (RFA) use in breast cancer is a developing area of research. There have been a number of published studies over the last decade, which explores the feasibility of minimally invasive techniques in breast cancer treatment. In this review, we will discuss the most recent data on radiofrequency ablation and examine the current methods, outcomes, complications, and limitations of RFA in breast cancer therapy. METHODS: Pub Med search for English Language articles on RFA in breast cancer. RESULTS: More than 25 studies were reviewed and we searched for number of tumors, average size, electrode used, if they successfully ablated the tumor, when the tumor was then resected and if the patients experienced any complication from the ablation. CONCLUSIONS: Radiofrequency ablation is an emerging minimally invasive therapy in small, localized breast cancer. Currently, no clinical trials have been published to directly compare RFA to the current standard of surgical resection. Ultimately, RFA will need clinical trials to evaluate oncologic outcomes involving long interval follow-up to determine survival, local control and disease progression before it becomes a reasonable alternative to surgical resection.
Entities:
Keywords:
Breast cancer; radiofrequency ablation; radiofrequency ablation (RFA)
Authors: Lee A Fleisher; Joshua A Beckman; Kenneth A Brown; Hugh Calkins; Elliot L Chaikof; Elliott Chaikof; Kirsten E Fleischmann; William K Freeman; James B Froehlich; Edward K Kasper; Judy R Kersten; Barbara Riegel; John F Robb; Sidney C Smith; Alice K Jacobs; Cynthia D Adams; Jeffrey L Anderson; Elliott M Antman; Christopher E Buller; Mark A Creager; Steven M Ettinger; David P Faxon; Valentin Fuster; Jonathan L Halperin; Loren F Hiratzka; Sharon A Hunt; Bruce W Lytle; Rick Nishimura; Joseph P Ornato; Richard L Page; Barbara Riegel; Lynn G Tarkington; Clyde W Yancy Journal: J Am Coll Cardiol Date: 2007-10-23 Impact factor: 24.094
Authors: F Izzo; R Thomas; P Delrio; M Rinaldo; P Vallone; A DeChiara; G Botti; G D'Aiuto; P Cortino; S A Curley Journal: Cancer Date: 2001-10-15 Impact factor: 6.860
Authors: Volodymyr M Nahirnyak; Eduardo G Moros; Petr Novák; V Suzanne Klimberg; Gal Shafirstein Journal: Int J Hyperthermia Date: 2010 Impact factor: 3.914
Authors: Vijay P Khatri; John P McGahan; Rajendra Ramsamooj; Stephen Griffey; John Brock; Michael Cronan; Stephen Wilkendorf Journal: Ann Surg Oncol Date: 2007-02-15 Impact factor: 5.344
Authors: Gábor Forrai; Eszter Kovács; Éva Ambrózay; Miklós Barta; Katalin Borbély; Zsolt Lengyel; Katalin Ormándi; Zoltán Péntek; Tasnádi Tünde; Éva Sebő Journal: Pathol Oncol Res Date: 2022-06-08 Impact factor: 2.874