| Literature DB >> 25083463 |
Víctor Manuel Vargas-Hernández1, Vm Vargas-Aguilar1, Mario Adanm Moreno-Eutimio1, Gustavo Acosta-Altamirano1, Jm Tovar-Rodriguez1.
Abstract
Breast Cancer is a heterogeneous disease, progressive, currently, are classified according to in pattern of gene expression luminal A, luminal B, basal and HER-2neu + and Triple-negative, 75% to 80% have receptors positive hormonal and 15% to 20% are positive for hER-2neu and 10% to 20% are triple negative, with hormone receptor negative and HER2-neu and their diagnostic is made by exclusion, the Metabolic Syndrome is related to a higher incidence of these cancers where the insulin-leptin axis-adiponectin are implicated in carcinogenesis.Entities:
Keywords: Breast cancer; adiponectin; carcinogenesis; diabetes mellitus; growth factors; leptin; metabolic syndrome; triple negative breast cancer
Year: 2013 PMID: 25083463 PMCID: PMC4115738 DOI: 10.3978/j.issn.2227-684X.2013.04.02
Source DB: PubMed Journal: Gland Surg ISSN: 2227-684X