Literature DB >> 25083309

Gastric metastasis of Merkel cell carcinoma, a rare cause of gastrointestinal bleeding: case report and review of the literature.

Malav P Parikh1, Salih Samo1, Venu Ganipisetti1, Sathish Krishnan1, Maulik Dhandha1, Margaret Yungbluth1, Walter R Glaws1.   

Abstract

Merkel cell carcinoma (MCC) is a highly aggressive cutaneous tumor of neuroendocrine origin. It is usually seen in elderly Caucasian males and occurs in sun exposed areas of the body. Diagnosis of MCC can be challenging and requires confirmation by immunohistochemical studies. It has an aggressive biological behavior with early local and distant metastasis and carries a dismal prognosis. However, metastasis of MCC to the stomach is very uncommon and rarely reported in the literature. We hereby describe a patient with gastric metastasis of MCC, who presented with upper gastrointestinal (GI) bleeding.

Entities:  

Keywords:  Merkel cell carcinoma (MCC); gastric metastasis; gastrointestinal bleeding (GI bleeding)

Year:  2014        PMID: 25083309      PMCID: PMC4110492          DOI: 10.3978/j.issn.2078-6891.2014.029

Source DB:  PubMed          Journal:  J Gastrointest Oncol        ISSN: 2078-6891


  22 in total

Review 1.  Merkel cell carcinoma: critical review with guidelines for multidisciplinary management.

Authors:  Christopher K Bichakjian; Lori Lowe; Christopher D Lao; Howard M Sandler; Carol R Bradford; Timothy M Johnson; Sandra L Wong
Journal:  Cancer       Date:  2007-07-01       Impact factor: 6.860

2.  Analysis of thyroid transcription factor-1 and cytokeratin 20 separates merkel cell carcinoma from small cell carcinoma of lung.

Authors:  A J Hanly; G W Elgart; M Jorda; J Smith; M Nadji
Journal:  J Cutan Pathol       Date:  2000-03       Impact factor: 1.587

3.  Immunostaining for thyroid transcription factor 1 and cytokeratin 20 aids the distinction of small cell carcinoma from Merkel cell carcinoma, but not pulmonary from extrapulmonary small cell carcinomas.

Authors:  W Cheuk; M Y Kwan; S Suster; J K Chan
Journal:  Arch Pathol Lab Med       Date:  2001-02       Impact factor: 5.534

4.  Cytokeratin 20: a marker for diagnosing Merkel cell carcinoma.

Authors:  M P Scott; K F Helm
Journal:  Am J Dermatopathol       Date:  1999-02       Impact factor: 1.533

Review 5.  Merkel cell carcinoma - recent advances in the biology, diagnostics and treatment.

Authors:  Piotr Czapiewski; Wojciech Biernat
Journal:  Int J Biochem Cell Biol       Date:  2014-05-05       Impact factor: 5.085

6.  Clonal integration of a polyomavirus in human Merkel cell carcinoma.

Authors:  Huichen Feng; Masahiro Shuda; Yuan Chang; Patrick S Moore
Journal:  Science       Date:  2008-01-17       Impact factor: 47.728

7.  Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features.

Authors:  Michelle Heath; Natalia Jaimes; Bianca Lemos; Arash Mostaghimi; Linda C Wang; Pablo F Peñas; Paul Nghiem
Journal:  J Am Acad Dermatol       Date:  2008-03       Impact factor: 11.527

Review 8.  Molecular pathogenesis of Merkel cell carcinoma.

Authors:  Roland Houben; David Schrama; Jürgen C Becker
Journal:  Exp Dermatol       Date:  2009-03       Impact factor: 3.960

Review 9.  Gastric metastasis of merkel cell cancer--uncommon complication of a rare neoplasm.

Authors:  N Gaurav Syal; Shyam Dang; James Rose; Chien Chen; Farshad Aduli
Journal:  J Ark Med Soc       Date:  2012-12

10.  Metastatic infiltrating ductal carcinoma of the breast to the colon: a case report and literature review.

Authors:  Salih Samo; Muhammed Sherid; Husein Husein; Samian Sulaiman; Jeffrey V Brower; Seth Alper; Margaret Yungbluth; John A Vainder
Journal:  Case Rep Gastrointest Med       Date:  2013-10-01
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  4 in total

1.  Merkel Cell Carcinoma Metastasis to Stomach: an Infrequent Culmination of a Rare Neoplasm.

Authors:  Jyoti Ramanath Kini; Rohit Tapadia; Suresh Shenoy
Journal:  J Gastrointest Cancer       Date:  2018-03

2.  Merkel Cell Carcinoma with Gastric Metastasis, a Rare Presentation: Case Report and Literature Review.

Authors:  Vittorio Durastante; Antonello Conte; Pier Paolo Brollo; Carlo Biddau; Michele Graziano; Vittorio Bresadola
Journal:  J Gastrointest Cancer       Date:  2022-03-07

3.  Anaemia due to gastric haemorrhage by a metastatic Merkel cell carcinoma.

Authors:  Jorge Santos-Juanes; Carmen Palomo; Luis Rodrigo; Iván Fernández-Vega
Journal:  Prz Gastroenterol       Date:  2015-04-28

4.  Partial Gastric Resection for Symptomatic Anemia following Diagnosis of Merkel Cell Carcinoma (MCC) of the Skin with Gastric Metastasis.

Authors:  Zachary Eagle; Francis Essien; George Shahin; Amia Jones; John McKee; Camille Elkins; Wassem Juakiem
Journal:  Clin Med Insights Case Rep       Date:  2022-10-03
  4 in total

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