Literature DB >> 25082861

Errant innate immune signaling in del(5q) MDS.

Daniel T Starczynowski1.   

Abstract

In this issue of Blood, Keerthivasan et al have identified that the deletion of mDia1, a chromosome 5q gene, contributes to myelodysplastic syndromes (MDSs) by increasing innate immune signaling in granulocytes.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 25082861      PMCID： PMC4118479          DOI： 10.1182/blood-2014-06-581728

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  8 in total

1.  NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies.

Authors:  Jimmy L Zhao; Dinesh S Rao; Mark P Boldin; Konstantin D Taganov; Ryan M O'Connell; David Baltimore
Journal:  Proc Natl Acad Sci U S A       Date:  2011-05-16       Impact factor: 11.205

2.  Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling.

Authors:  T Tominaga; E Sahai; P Chardin; F McCormick; S A Courtneidge; A S Alberts
Journal:  Mol Cell       Date:  2000-01       Impact factor: 17.970

Review 3.  Deletion 5q in myelodysplastic syndrome: a paradigm for the study of hemizygous deletions in cancer.

Authors:  B L Ebert
Journal:  Leukemia       Date:  2009-03-26       Impact factor: 11.528

4.  Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.

Authors:  Daniel T Starczynowski; Florian Kuchenbauer; Bob Argiropoulos; Sandy Sung; Ryan Morin; Andrew Muranyi; Martin Hirst; Donna Hogge; Marco Marra; Richard A Wells; Rena Buckstein; Wan Lam; R Keith Humphries; Aly Karsan
Journal:  Nat Med       Date:  2009-11-08       Impact factor: 53.440

5.  Aberrant overexpression of CD14 on granulocytes sensitizes the innate immune response in mDia1 heterozygous del(5q) MDS.

Authors:  Ganesan Keerthivasan; Yang Mei; Baobing Zhao; Ling Zhang; Chad E Harris; Juehua Gao; Ashley A Basiorka; Matthew J Schipma; James McElherne; Jing Yang; Amit K Verma; Andrea Pellagatti; Jacqueline Boultwood; Alan F List; David A Williams; Peng Ji
Journal:  Blood       Date:  2014-06-02       Impact factor: 22.113

6.  Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome.

Authors:  Garrett W Rhyasen; Lyndsey Bolanos; Jing Fang; Andres Jerez; Mark Wunderlich; Carmela Rigolino; Lesley Mathews; Marc Ferrer; Noel Southall; Rajarshi Guha; Jonathan Keller; Craig Thomas; Levi J Beverly; Agostino Cortelezzi; Esther N Oliva; Maria Cuzzola; Jaroslaw P Maciejewski; James C Mulloy; Daniel T Starczynowski
Journal:  Cancer Cell       Date:  2013-07-08       Impact factor: 31.743

7.  MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice.

Authors:  Jimmy L Zhao; Dinesh S Rao; Ryan M O'Connell; Yvette Garcia-Flores; David Baltimore
Journal:  Elife       Date:  2013-05-21       Impact factor: 8.140

Review 8.  DAMPening inflammation by modulating TLR signalling.

Authors:  A M Piccinini; K S Midwood
Journal:  Mediators Inflamm       Date:  2010-07-13       Impact factor: 4.711
  8 in total
  2 in total

1.  Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations.

Authors:  Stanley Chun-Wei Lee; Khrystyna North; Eunhee Kim; Eunjung Jang; Esther Obeng; Sydney X Lu; Bo Liu; Daichi Inoue; Akihide Yoshimi; Michelle Ki; Mirae Yeo; Xiao Jing Zhang; Min Kyung Kim; Hana Cho; Young Rock Chung; Justin Taylor; Benjamin H Durham; Young Joon Kim; Alessandro Pastore; Sebastien Monette; James Palacino; Michael Seiler; Silvia Buonamici; Peter G Smith; Benjamin L Ebert; Robert K Bradley; Omar Abdel-Wahab
Journal:  Cancer Cell       Date:  2018-08-13       Impact factor: 31.743

2.  Bone marrow-confined IL-6 signaling mediates the progression of myelodysplastic syndromes to acute myeloid leukemia.

Authors:  Yang Mei; Kehan Ren; Yijie Liu; Annabel Ma; Zongjun Xia; Xu Han; Ermin Li; Hamza Tariq; Haiyan Bao; Xinshu Xie; Cheng Zou; Dingxiao Zhang; Zhaofeng Li; Lili Dong; Amit Verma; Xinyan Lu; Yasmin Abaza; Jessica K Altman; Madina Sukhanova; Jing Yang; Peng Ji
Journal:  J Clin Invest       Date:  2022-09-01       Impact factor: 19.456
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.