Literature DB >> 25082197

A growing role for Aurora A in chromosome instability.

Ana R R Maia1, Roy G H P van Heesbeen1, René H Medema1.   

Abstract

Chromosome instability is a major hallmark of cancer, but its molecular causes are still poorly understood. A study now describes how genetic alterations frequently found in colorectal cancer increase microtubule assembly rates during mitosis and promote chromosome instability.

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Year:  2014        PMID： 25082197     DOI： 10.1038/ncb3018

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  15 in total

Review 1.  Cancer chromosomal instability: therapeutic and diagnostic challenges.

Authors:  Nicholas McGranahan; Rebecca A Burrell; David Endesfelder; Marco R Novelli; Charles Swanton
Journal:  EMBO Rep       Date:  2012-06-01       Impact factor: 8.807

2.  The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells.

Authors:  Ailine Stolz; Norman Ertych; Anne Kienitz; Celia Vogel; Verena Schneider; Barbara Fritz; Ralf Jacob; Gunnar Dittmar; Wilko Weichert; Iver Petersen; Holger Bastians
Journal:  Nat Cell Biol       Date:  2010-04-04       Impact factor: 28.824

3.  Aurora kinases and spindle assembly: variations on a common theme?

Authors:  Vladimir Joukov
Journal:  Cell Cycle       Date:  2011-03-15       Impact factor: 4.534

4.  Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models.

Authors:  Dongwei Zhang; Toru Hirota; Tomotoshi Marumoto; Michio Shimizu; Naoko Kunitoku; Takashi Sasayama; Yoshimi Arima; Liping Feng; Misao Suzuki; Motohiro Takeya; Hideyuki Saya
Journal:  Oncogene       Date:  2004-11-18       Impact factor: 9.867

Review 5.  Molecular origins of cancer: Molecular basis of colorectal cancer.

Authors:  Sanford D Markowitz; Monica M Bertagnolli
Journal:  N Engl J Med       Date:  2009-12-17       Impact factor: 91.245

6.  Effects of aneuploidy on cellular physiology and cell division in haploid yeast.

Authors:  Eduardo M Torres; Tanya Sokolsky; Cheryl M Tucker; Leon Y Chan; Monica Boselli; Maitreya J Dunham; Angelika Amon
Journal:  Science       Date:  2007-08-17       Impact factor: 47.728

7.  Aurora A overexpression induces cellular senescence in mammary gland hyperplastic tumors developed in p53-deficient mice.

Authors:  D Zhang; T Shimizu; N Araki; T Hirota; M Yoshie; K Ogawa; N Nakagata; M Takeya; H Saya
Journal:  Oncogene       Date:  2008-03-31       Impact factor: 9.867

Review 8.  The significance of unstable chromosomes in colorectal cancer.

Authors:  Harith Rajagopalan; Martin A Nowak; Bert Vogelstein; Christoph Lengauer
Journal:  Nat Rev Cancer       Date:  2003-09       Impact factor: 60.716

Review 9.  A systematic review of treatment guidelines for metastatic colorectal cancer.

Authors:  M S Edwards; S D Chadda; Z Zhao; B L Barber; D P Sykes
Journal:  Colorectal Dis       Date:  2012-02       Impact factor: 3.788

Review 10.  Merotelic kinetochore attachment: causes and effects.

Authors:  Juraj Gregan; Silvia Polakova; Lijuan Zhang; Iva M Tolić-Nørrelykke; Daniela Cimini
Journal:  Trends Cell Biol       Date:  2011-02-08       Impact factor: 20.808
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  5 in total

1.  Potential functional variants in SMC2 and TP53 in the AURORA pathway genes and risk of pancreatic cancer.

Authors:  Yun Feng; Hongliang Liu; Bensong Duan; Zhensheng Liu; James Abbruzzese; Kyle M Walsh; Xuefeng Zhang; Qingyi Wei
Journal:  Carcinogenesis       Date:  2019-06-10       Impact factor: 4.944

2.  Aurora kinase A inhibition induces synthetic lethality in SMAD4-deficient colorectal cancer cells via spindle assembly checkpoint activation.

Authors:  Changxiang Shi; Shishi Tao; Guowen Ren; Eun Ju Yang; Xiaodong Shu; Pui Kei Mou; Yifan Liu; Yongjun Dang; Xiaoling Xu; Joong Sup Shim
Journal:  Oncogene       Date:  2022-04-07       Impact factor: 8.756

3.  Therapeutic Rationale to Target Highly Expressed Aurora kinase A Conferring Poor Prognosis in Cholangiocarcinoma.

Authors:  Xiwei Ding; Tianlu Huang; Chunyan Peng; Keun Soo Ahn; Jesper B Andersen; Monika Lewinska; Yu Cao; Guifang Xu; Gang Chen; Bo Kong; Helmut Friess; Shanshan Shen; Lewis R Roberts; Lei Wang; Xiaoping Zou
Journal:  J Cancer       Date:  2020-02-03       Impact factor: 4.207

4.  Neutrophil Extracellular Traps Facilitate A549 Cell Invasion and Migration in a Macrophage-Maintained Inflammatory Microenvironment.

Authors:  Lemeng Zhang; Huifang Yi; Jianhua Chen; Haitao Li; Yongzhong Luo; Tianli Cheng; Hua Yang; Zhou Jiang; Changqie Pan
Journal:  Biomed Res Int       Date:  2022-01-06       Impact factor: 3.411

Review 5.  Ubiquitin-Mediated Degradation of Aurora Kinases.

Authors:  Catherine Lindon; Rhys Grant; Mingwei Min
Journal:  Front Oncol       Date:  2016-01-18       Impact factor: 6.244
  5 in total

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