| Literature DB >> 25082130 |
A Mosquera Gorostidi1, A Justo Ranera2, S E Zakirian Denis2, N González Temprano2, M Sagaseta de Ilúrdoz Uranga2, J Molina Garicano2.
Abstract
Pheochromocytomas and paragangliomas are rare neuroendocrine tumors in children and most of them are sporadic. However, they represent the most common endocrine tumor in childhood, and hereditary tumor syndromes are most relevant in these age. Advances in genetic, biochemistry and imaging techniques have revised the management of these tumors; thus A biochemical study should be always initiated once the clinical diagnosis is suspected, followed by imaging and molecular studies, particularly in the context of known familial disease. The diagnostic and therapeutic features are reviewed after the presentation of two clinical cases, where the second one is a patient with type 1 Neurofibromatosis.Entities:
Keywords: Catecholamines; Catecolaminas; Children; Feocromocitoma; Metanefrinas; Metanephrines; Paraganglioma; Pediátricos; Pheochromocytoma
Mesh:
Year: 2014 PMID: 25082130 DOI: 10.1016/j.anpedi.2014.06.018
Source DB: PubMed Journal: An Pediatr (Barc) ISSN: 1695-4033 Impact factor: 1.500