| Literature DB >> 25081023 |
Gui-Hong Yu1, Guang-Wei Wu, Tian-Jiao Zhu, Qian-Qun Gu, De-Hai Li.
Abstract
Two new fungal hybrid polyketides, cladosins F (1) and G (2), with rare 6(3)-enamino-8,10-dihydroxy-tetraketide system were discovered from the deep-sea-derived fungus Cladosporium sphaerospermum 2005-01-E3 guided by OSMAC approach. Their structures were elucidated on the basis of comprehensive spectroscopic analyses, and cytotoxicity, antitubercular, anti-influenza A H1N1 virus, and NF-κB inhibitory activities were evaluated.Entities:
Keywords: Cladosporium sphaerospermum; cladosin; deep-sea-derived fungus; fungal hybrid polyketide
Mesh：
Substances：
Year: 2014 PMID： 25081023 DOI： 10.1080/10286020.2014.940330
Source DB: PubMed Journal: J Asian Nat Prod Res ISSN： 1028-6020 Impact factor: 1.569