Literature DB >> 2508043

[Effect of low-frequency electric stimulation of the dentate nucleus of the cerebellum on foci of epileptic activity].

A A Shandra, L S Godlevskiĭ.   

Abstract

It was demonstrated in acute experiments on cats that low-frequency (7-12 Hz) electrical stimulation of the dentate nucleus of the cerebellum induces the formation of ictal discharges in foci of powerful epileptic activity produced in the brain cortex by application of penicillin solution. Ictal discharges were also provoked under the effect of electrical stimulation (7-12 Hz) of the ventrolateral nucleus of the thalamus. Destruction of the ventrolateral nucleus abolished the effect of ictal discharge facilitation induced by stimulation of the dentate nucleus. The results are discussed from the standpoint of increasing the efficacy of the stimulation method for arresting the epileptic syndrome.

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Year:  1989        PMID: 2508043

Source DB:  PubMed          Journal:  Patol Fiziol Eksp Ter        ISSN: 0031-2991


  1 in total

1.  The effects of electrical stimulation of the paleocerebellar cortex on penicillin-induced convulsive activity in rats.

Authors:  L S Godlevskii; K I Stepanenko; B A Lobasyuk; E V Sarakhan; L M Bobkova
Journal:  Neurosci Behav Physiol       Date:  2004-10
  1 in total

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