Literature DB >> 25080196

Xenortide Biosynthesis by Entomopathogenic Xenorhabdus nematophila.

Daniela Reimer1, Friederike I Nollmann1, Katharina Schultz1, Marcel Kaiser2, Helge B Bode1.   

Abstract

The biosynthesis gene cluster of the xenortides and a new derivative, xenortide D, which is produced in only trace amounts, was identified in Xenorhabdus nematophila. The structure of xenortide D was elucidated using a combination of labeling experiments followed by MS analysis and was confirmed by synthesis. Bioactivity tests revealed a weak activity of tryptamine-carrying xenortides against Plasmodium falciparum and Trypanosoma brucei.

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Year:  2014        PMID： 25080196     DOI： 10.1021/np500390b

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  8 in total

1.  Role of secondary metabolites in establishment of the mutualistic partnership between Xenorhabdus nematophila and the entomopathogenic nematode Steinernema carpocapsae.

Authors:  Swati Singh; David Orr; Emmanuel Divinagracia; Joseph McGraw; Kellen Dorff; Steven Forst
Journal:  Appl Environ Microbiol       Date:  2014-11-14       Impact factor: 4.792

Review 2.  Recent highlights in biosynthesis research using stable isotopes.

Authors:  Jan Rinkel; Jeroen S Dickschat
Journal:  Beilstein J Org Chem       Date:  2015-12-09       Impact factor: 2.883

3.  A New Member of the Growing Family of Contact-Dependent Growth Inhibition Systems in Xenorhabdus doucetiae.

Authors:  Jean-Claude Ogier; Bernard Duvic; Anne Lanois; Alain Givaudan; Sophie Gaudriault
Journal:  PLoS One       Date:  2016-12-01       Impact factor: 3.240

4.  The Global Regulators Lrp, LeuO, and HexA Control Secondary Metabolism in Entomopathogenic Bacteria.

Authors:  Yvonne Engel; Carina Windhorst; Xiaojun Lu; Heidi Goodrich-Blair; Helge B Bode
Journal:  Front Microbiol       Date:  2017-02-17       Impact factor: 5.640

Review 5.  Nematophilic bacteria associated with entomopathogenic nematodes and drug development of their biomolecules.

Authors:  Ryan Musumba Awori
Journal:  Front Microbiol       Date:  2022-09-15       Impact factor: 6.064

6.  Phenylethylamides derived from bacterial secondary metabolites specifically inhibit an insect serotonin receptor.

Authors:  Ariful Hasan; Hyun-Suk Yeom; Jaewook Ryu; Helge B Bode; Yonggyun Kim
Journal:  Sci Rep       Date:  2019-12-30       Impact factor: 4.379

Review 7.  Antimicrobial Peptides: Novel Source and Biological Function With a Special Focus on Entomopathogenic Nematode/Bacterium Symbiotic Complex.

Authors:  Surajit De Mandal; Amrita Kumari Panda; Chandran Murugan; Xiaoxia Xu; Nachimuthu Senthil Kumar; Fengliang Jin
Journal:  Front Microbiol       Date:  2021-07-14       Impact factor: 5.640

Review 8.  Type Strains of Entomopathogenic Nematode-Symbiotic Bacterium Species, Xenorhabdus szentirmaii (EMC) and X. budapestensis (EMA), Are Exceptional Sources of Non-Ribosomal Templated, Large-Target-Spectral, Thermotolerant-Antimicrobial Peptides (by Both), and Iodinin (by EMC).

Authors:  András Fodor; Maxime Gualtieri; Matthias Zeller; Eustachio Tarasco; Michael G Klein; Andrea M Fodor; Leroy Haynes; Katalin Lengyel; Steven A Forst; Ghazala M Furgani; Levente Karaffa; Tibor Vellai
Journal:  Pathogens       Date:  2022-03-11
  8 in total

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